Table 1 KIR ligands carried by the... | American Society of Hematology

Table 1

KIR ligands carried by the NK-cell donor (P61) or by different mDCs and T-cell targets

	HLA class I epitope
	C1*	C2*	HLA-Bw4 T80†	HLA-Bw4 I80†	HLA-Bw6†	HLA-A Bw4+*
P61	P	A	P	A	A	P
GF	A	P	P	A	P	A
SC	P	P	A	P	A	P
RB	A	P	A	P	A	A
CV	P	P	A	P	A	A

	HLA class I epitope
	C1*	C2*	HLA-Bw4 T80†	HLA-Bw4 I80†	HLA-Bw6†	HLA-A Bw4+*
P61	P	A	P	A	A	P
GF	A	P	P	A	P	A
SC	P	P	A	P	A	P
RB	A	P	A	P	A	A
CV	P	P	A	P	A	A

DNA of the indicated samples have been tested by sequence-specific polymorphism PCR (SSP-PCR) approach to define KIR ligands. Results obtained using set of primers that allowed to detect the presence (P) or the absence (A) of HLA-C alleles coding for C1 (HLA-C N80) or C2 (HLA-C K80) epitope, of HLA-Bw4 alleles carrying a threonine (T) or a isoleucine (I) at position 80, and of HLA-A alleles characterized by the Bw4 public epitope.

†

RNA of the indicated samples have been tested by SSP-PCR approach to define KIR ligands. Results obtained using set of primers that selectively amplify HLA-B alleles sharing Bw6 epitope.

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