Table 1 Lack of CD114 expression... | American Society of Hematology

Table 1

Lack of CD114 expression distinguishes bona fide HSC from transiently reconstituting multilineage progenitors

Time	Subfraction	Engraft	No Engraft	Statistic
Week 6	CD114^neg/lo	10	4	0.21
	CD114^pos	4	6
Week 14	CD114^neg/lo	12	2	0.002
	CD114^hi	2	8

Time	Subfraction	Engraft	No Engraft	Statistic
Week 6	CD114^neg/lo	10	4	0.21
	CD114^pos	4	6
Week 14	CD114^neg/lo	12	2	0.002
	CD114^hi	2	8

The presence of human engraftment in the bone marrow of NOD/SCID/IL-2Rγ^null (NSG) mice transplanted with either CD114^neg/lo or CD114^pos subfractions of the human HSC compartment was determined 6 and 14 weeks after transplantation. No statistically significant difference in engraftment was observed at 6 weeks; however, by 14 weeks, engraftment was markedly enriched in the CD114^neg/lo subfraction. The Fisher exact, 2-tailed test was used for statistic calculation.

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