| Complete response (CR) | A platelet count ≥ 100 × 109/L measured on 2 occasions > 7 days apart and the absence of bleeding. |
| Response (R) | A platelet count ≥ 30 × 109/L and a greater than 2-fold increase in platelet count from baseline measured on 2 occasions > 7 days apart and the absence of bleeding. |
| No response (NR) | A platelet count < 30 × 109/L or a less than 2-fold increase in platelet count from baseline or the presence of bleeding. Platelet count must be measured on 2 occasions more than a day apart. |
| Loss of complete response | A platelet count < 100 × 109/L measured on 2 occasions more than a day apart and/or the presence of bleeding. |
| Loss of response | A platelet count < 30 × 109/L or a less than 2-fold increase in platelet count from baseline or the presence of bleeding. Platelet count must be measured on 2 occasions more than a day apart. |
| Complete response (CR) | A platelet count ≥ 100 × 109/L measured on 2 occasions > 7 days apart and the absence of bleeding. |
| Response (R) | A platelet count ≥ 30 × 109/L and a greater than 2-fold increase in platelet count from baseline measured on 2 occasions > 7 days apart and the absence of bleeding. |
| No response (NR) | A platelet count < 30 × 109/L or a less than 2-fold increase in platelet count from baseline or the presence of bleeding. Platelet count must be measured on 2 occasions more than a day apart. |
| Loss of complete response | A platelet count < 100 × 109/L measured on 2 occasions more than a day apart and/or the presence of bleeding. |
| Loss of response | A platelet count < 30 × 109/L or a less than 2-fold increase in platelet count from baseline or the presence of bleeding. Platelet count must be measured on 2 occasions more than a day apart. |
Based on the recommendations of the International Working Group.7