Human PU.1-rescued PU.1−/− mice have normal peripheral blood parameters
| . | BAC−PU.1+/+ . | #1 BAC+PU.1−/− . | #55 BAC+PU.1−/− . |
|---|---|---|---|
| White blood cell count, × 103/mm3 | 13.06 ± 1.95 | 10.78 ± 1.26 | 10.5 ± 1.33 |
| Red blood cell count, × 106/mm3 | 12.44 ± 0.76 | 13.72 ± 4.44 | 15.1 ± 1.26 |
| Hemoglobin level, g/dL | 16.5 ± 0.81 | 19.2 ± 5.93 | 10.75 ± 1.73 |
| Lymphocytes, % | 72.76 ± 4.88 | 80 ± 3.25 | 79.4 ± 4.28 |
| Granulocytes, % | 19.66 ± 4.34 | 13.62 ± 2.9 | 15.42 ± 3.9 |
| Monocytes, % | 7.78 ± 0.93 | 6.42 ± 1.39 | 5.66 ± 1.23 |
| . | BAC−PU.1+/+ . | #1 BAC+PU.1−/− . | #55 BAC+PU.1−/− . |
|---|---|---|---|
| White blood cell count, × 103/mm3 | 13.06 ± 1.95 | 10.78 ± 1.26 | 10.5 ± 1.33 |
| Red blood cell count, × 106/mm3 | 12.44 ± 0.76 | 13.72 ± 4.44 | 15.1 ± 1.26 |
| Hemoglobin level, g/dL | 16.5 ± 0.81 | 19.2 ± 5.93 | 10.75 ± 1.73 |
| Lymphocytes, % | 72.76 ± 4.88 | 80 ± 3.25 | 79.4 ± 4.28 |
| Granulocytes, % | 19.66 ± 4.34 | 13.62 ± 2.9 | 15.42 ± 3.9 |
| Monocytes, % | 7.78 ± 0.93 | 6.42 ± 1.39 | 5.66 ± 1.23 |
Blood was obtained from age-matched mice (12-16 weeks) by tail puncture. Values indicate means ± SDs of the indicated genotypes; n = 5 each.