Table 1 Rescue of the lethal PU.1 −/−... | American Society of Hematology

Table 1

Rescue of the lethal PU.1^−/− phenotype by transgenic expression of human PU.1

Transgenic line	No. of mice	BAC	Mouse PU.1 allele
Transgenic line	No. of mice	BAC	+/+	+/−	−/−
#1	137	−	14	37	0
		+	17	50	19
#55	126	−	20	38	0
		+	17	32	19

Transgenic line	No. of mice	BAC	Mouse PU.1 allele
Transgenic line	No. of mice	BAC	+/+	+/−	−/−
#1	137	−	14	37	0
		+	17	50	19
#55	126	−	20	38	0
		+	17	32	19

Genotyping of offspring resulting from mating of BAC⁺PU.1^+/− and BAC⁻PU.1^+/− parents were determined by PCR at weaning.