Table 1

Mice reconstituted with Fancc−/−;Fancg−/− donor cells have an increased risk of myeloid malignancy

Donor cell genotypeMalignancy
WT 0/16 
Fancc−/− 0/15 
Fancg−/− 0/16 
Fancc−/−;Fancg−/− 9/17 
Donor cell genotypeMalignancy
WT 0/16 
Fancc−/− 0/15 
Fancg−/− 0/16 
Fancc−/−;Fancg−/− 9/17 

This summary represents all of the data from 2 cohorts of competitive repopulation transplants and 1 cohort of non-competitive transplants.

WT indicates wild-type.

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