Suggested indications for allo-HSCT among young adults with AML in first complete remission
| Cytogenetic risk factor . | HLA-matched sibling . | MUD/haplo/cord . |
|---|---|---|
| Favorable, all except | No | No |
| c-KIT | Yes | Possible |
| Intermediate, all except | Yes | Possible |
| NPM+/ FLT3-ITD− | Possible | No |
| Biallelic CEBPA+/ FLT3-ITD− | Possible | No |
| FLT3-ITD+ | Yes | Yes |
| Unfavorable | Yes | Yes |
| Cytogenetic risk factor . | HLA-matched sibling . | MUD/haplo/cord . |
|---|---|---|
| Favorable, all except | No | No |
| c-KIT | Yes | Possible |
| Intermediate, all except | Yes | Possible |
| NPM+/ FLT3-ITD− | Possible | No |
| Biallelic CEBPA+/ FLT3-ITD− | Possible | No |
| FLT3-ITD+ | Yes | Yes |
| Unfavorable | Yes | Yes |
Adapted from Rowe.36