Studies evaluating the association between TF-positive MPs and VTE in patients with cancer
| Study . | Method . | Patients . | Time of follow-up . | Association between MP TF and VTE? . |
|---|---|---|---|---|
| Retrospective | ||||
| Tesselaar, 200758 | MP TF activity assay | 7 late stage pancreatic and breast cancer patients with VTE | n/a | Yes |
| 33 late stage pancreatic and breast cancer patients without VTE | ||||
| Zwicker, 200966 | Impedance-based flow cytometry | 30 cancer patients with VTE | n/a | Yes |
| 60 case-matched cancer patients without VTE | ||||
| Tesselaar, 200991 | MP TF activity assay | 51 cancer patients with VTE | n/a | Yes |
| 49 case-matched cancer patients without VTE | ||||
| Manly, 201093 | MP TF activity | 53 cancer patients with VTE | n/a | Yes |
| 13 cancer patients without VTE | ||||
| Campello, 201163 | Flow cytometry | 30 cancer patients with VTE | n/a | Yes |
| 30 case-matched cancer patients without VTE | ||||
| Prospective | ||||
| Khorana, 200856 | MP TF activity | 2 pancreatic cancer patients who develop VTE | Every 4 wk for 20 wk | Yes |
| TF enzyme-linked immunosorbent assay | 8 pancreatic cancer patients without VTE | |||
| Zwicker, 200966 | Impedance-based flow cytometry | 4 cancer patients who develop VTE | 1 y | Yes |
| 56 cancer patients without VTE | ||||
| Bharthuar, 201097 | MP TF activity | 52 Pancreaticobiliary cancer patients who develop VTE | 6 mo | Yes |
| 65 Pancreaticobiliary cancer patients without VTE | ||||
| Auwerda, 201194 | MP TF activity | 15 multiple myeloma patients undergoing chemotherapy with VTE | Not specified | No |
| 107 multiple myeloma patients undergoing chemotherapy without VTE | ||||
| Van Doormaal, 201264 | MP TF activityMP-dependent fibrin generation flow cytometryTF enzyme-linked immunosorbent assay | 5 cancer patients who develop VTE (3 pancreatic)38 cancer patients without VTE (10 pancreatic) | 6 mo | Yes by functional assayNo by antigen assay |
| Thaler, 201260 | MP TF activity | 49 cancer patients who develop VTE (12 pancreatic) | 2 y | No |
| 299 cancer patients without VTE (48 pancreatic) | ||||
| Sartori, 201381 | Flow cytometry | 11 glioblastoma patients who develop VTE | 7 mo | Yes |
| 50 glioblastoma patients without VTE |
| Study . | Method . | Patients . | Time of follow-up . | Association between MP TF and VTE? . |
|---|---|---|---|---|
| Retrospective | ||||
| Tesselaar, 200758 | MP TF activity assay | 7 late stage pancreatic and breast cancer patients with VTE | n/a | Yes |
| 33 late stage pancreatic and breast cancer patients without VTE | ||||
| Zwicker, 200966 | Impedance-based flow cytometry | 30 cancer patients with VTE | n/a | Yes |
| 60 case-matched cancer patients without VTE | ||||
| Tesselaar, 200991 | MP TF activity assay | 51 cancer patients with VTE | n/a | Yes |
| 49 case-matched cancer patients without VTE | ||||
| Manly, 201093 | MP TF activity | 53 cancer patients with VTE | n/a | Yes |
| 13 cancer patients without VTE | ||||
| Campello, 201163 | Flow cytometry | 30 cancer patients with VTE | n/a | Yes |
| 30 case-matched cancer patients without VTE | ||||
| Prospective | ||||
| Khorana, 200856 | MP TF activity | 2 pancreatic cancer patients who develop VTE | Every 4 wk for 20 wk | Yes |
| TF enzyme-linked immunosorbent assay | 8 pancreatic cancer patients without VTE | |||
| Zwicker, 200966 | Impedance-based flow cytometry | 4 cancer patients who develop VTE | 1 y | Yes |
| 56 cancer patients without VTE | ||||
| Bharthuar, 201097 | MP TF activity | 52 Pancreaticobiliary cancer patients who develop VTE | 6 mo | Yes |
| 65 Pancreaticobiliary cancer patients without VTE | ||||
| Auwerda, 201194 | MP TF activity | 15 multiple myeloma patients undergoing chemotherapy with VTE | Not specified | No |
| 107 multiple myeloma patients undergoing chemotherapy without VTE | ||||
| Van Doormaal, 201264 | MP TF activityMP-dependent fibrin generation flow cytometryTF enzyme-linked immunosorbent assay | 5 cancer patients who develop VTE (3 pancreatic)38 cancer patients without VTE (10 pancreatic) | 6 mo | Yes by functional assayNo by antigen assay |
| Thaler, 201260 | MP TF activity | 49 cancer patients who develop VTE (12 pancreatic) | 2 y | No |
| 299 cancer patients without VTE (48 pancreatic) | ||||
| Sartori, 201381 | Flow cytometry | 11 glioblastoma patients who develop VTE | 7 mo | Yes |
| 50 glioblastoma patients without VTE |
n/a, not applicable.