Analysis of transgenic mice at 4 to 6 weeks of age
Genotype . | White blood cells, ×103/μL . | Red blood cells, ×106/μL . | Reticulocytes, % . | Automated hematocrit, % . | Spun hematocrit, % . | Hemoglobin, g/dL . | Mean corpuscular volume, fl . | Platelets, ×103/μL . |
---|---|---|---|---|---|---|---|---|
+/+ Control (n = 5) | 6.3 ± 2.3 | 10.07 ± 0.54 | 1.85 ± 0.32 | 50.68 ± 2.9 | 51.2 ± 1.3 | 16.3 ± 0.77 | 47.2 ± 0.36 | 1714 ± 172.4 |
RPS19/+ wild-type (n = 8) | 4.37 ± 1.1 | 9.98 ± 0.43 | 1.67 ± 0.42 | 49.20 ± 1.8 | 50.7 ± 2.0 | 16.2 ± 0.55 | 46.8 ± 0.47 | 1400 ± 91.2 |
P | .138 | .751 | .731 | .352 | .578 | .714 | .44 | .011* |
+/+ Cre+ (n = 5-7) | 6.48 ± 1.84 | 10.47 ± 0.65 | 1.9 ± 0.3 | 51.2 ± 1.6 | 51.27 ± 2.41 | 16.53 ± 0.81 | 47.87 ± 0.8 | 1115 ± 287.8 |
RPS19R62W/+ Cre+ (n = 8) | 5.10 ± 4.04 | 9.21 ± 0.39 | 0.19 ± 0.16 | 47.17 ± 3.0 | 47.19 ± 2.20 | 15.34 ± 0.31 | 50.71 ± 2.06 | 835.1 ± 119.4 |
P | .88 | .001 | < .001 | .026 | .018 | .002 | .044 | .025* |
Genotype . | White blood cells, ×103/μL . | Red blood cells, ×106/μL . | Reticulocytes, % . | Automated hematocrit, % . | Spun hematocrit, % . | Hemoglobin, g/dL . | Mean corpuscular volume, fl . | Platelets, ×103/μL . |
---|---|---|---|---|---|---|---|---|
+/+ Control (n = 5) | 6.3 ± 2.3 | 10.07 ± 0.54 | 1.85 ± 0.32 | 50.68 ± 2.9 | 51.2 ± 1.3 | 16.3 ± 0.77 | 47.2 ± 0.36 | 1714 ± 172.4 |
RPS19/+ wild-type (n = 8) | 4.37 ± 1.1 | 9.98 ± 0.43 | 1.67 ± 0.42 | 49.20 ± 1.8 | 50.7 ± 2.0 | 16.2 ± 0.55 | 46.8 ± 0.47 | 1400 ± 91.2 |
P | .138 | .751 | .731 | .352 | .578 | .714 | .44 | .011* |
+/+ Cre+ (n = 5-7) | 6.48 ± 1.84 | 10.47 ± 0.65 | 1.9 ± 0.3 | 51.2 ± 1.6 | 51.27 ± 2.41 | 16.53 ± 0.81 | 47.87 ± 0.8 | 1115 ± 287.8 |
RPS19R62W/+ Cre+ (n = 8) | 5.10 ± 4.04 | 9.21 ± 0.39 | 0.19 ± 0.16 | 47.17 ± 3.0 | 47.19 ± 2.20 | 15.34 ± 0.31 | 50.71 ± 2.06 | 835.1 ± 119.4 |
P | .88 | .001 | < .001 | .026 | .018 | .002 | .044 | .025* |
Both values are within the normal range.