Table 3

Analysis of transgenic mice at 4 to 6 weeks of age

GenotypeWhite blood cells, ×103/μLRed blood cells, ×106/μLReticulocytes, %Automated hematocrit, %Spun hematocrit, %Hemoglobin, g/dLMean corpuscular volume, flPlatelets, ×103/μL
+/+ Control (n = 5) 6.3 ± 2.3 10.07 ± 0.54 1.85 ± 0.32 50.68 ± 2.9 51.2 ± 1.3 16.3 ± 0.77 47.2 ± 0.36 1714 ± 172.4 
RPS19/+ wild-type (n = 8) 4.37 ± 1.1 9.98 ± 0.43 1.67 ± 0.42 49.20 ± 1.8 50.7 ± 2.0 16.2 ± 0.55 46.8 ± 0.47 1400 ± 91.2 
P .138 .751 .731 .352 .578 .714 .44 .011* 
+/+ Cre+ (n = 5-7) 6.48 ± 1.84 10.47 ± 0.65 1.9 ± 0.3 51.2 ± 1.6 51.27 ± 2.41 16.53 ± 0.81 47.87 ± 0.8 1115 ± 287.8 
RPS19R62W/+ Cre+ (n = 8) 5.10 ± 4.04 9.21 ± 0.39 0.19 ± 0.16 47.17 ± 3.0 47.19 ± 2.20 15.34 ± 0.31 50.71 ± 2.06 835.1 ± 119.4 
P .88 .001 < .001 .026 .018 .002 .044 .025* 
GenotypeWhite blood cells, ×103/μLRed blood cells, ×106/μLReticulocytes, %Automated hematocrit, %Spun hematocrit, %Hemoglobin, g/dLMean corpuscular volume, flPlatelets, ×103/μL
+/+ Control (n = 5) 6.3 ± 2.3 10.07 ± 0.54 1.85 ± 0.32 50.68 ± 2.9 51.2 ± 1.3 16.3 ± 0.77 47.2 ± 0.36 1714 ± 172.4 
RPS19/+ wild-type (n = 8) 4.37 ± 1.1 9.98 ± 0.43 1.67 ± 0.42 49.20 ± 1.8 50.7 ± 2.0 16.2 ± 0.55 46.8 ± 0.47 1400 ± 91.2 
P .138 .751 .731 .352 .578 .714 .44 .011* 
+/+ Cre+ (n = 5-7) 6.48 ± 1.84 10.47 ± 0.65 1.9 ± 0.3 51.2 ± 1.6 51.27 ± 2.41 16.53 ± 0.81 47.87 ± 0.8 1115 ± 287.8 
RPS19R62W/+ Cre+ (n = 8) 5.10 ± 4.04 9.21 ± 0.39 0.19 ± 0.16 47.17 ± 3.0 47.19 ± 2.20 15.34 ± 0.31 50.71 ± 2.06 835.1 ± 119.4 
P .88 .001 < .001 .026 .018 .002 .044 .025* 
*

Both values are within the normal range.

Close Modal

or Create an Account

Close Modal
Close Modal