Most common (> 5% overall) drug-related AEs by dose group
| . | < 20 mg/kg/d (n = 75), no. (%) . | ≥ 20-< 30 mg/kg/d (n = 41), no. (%) . | All (n = 116), no. (%) . |
|---|---|---|---|
| Nausea | 19 (25.3) | 7 (17.1) | 26 (22.4) |
| Diarrhea | 10 (13.3) | 8 (19.5) | 18 (15.5) |
| Rash | 9 (12.0) | 4 (9.8) | 13 (11.2) |
| Vomiting | 9 (12.0) | 1 (2.4) | 10 (8.6) |
| Dyspepsia | 8 (10.7) | 1 (2.4) | 9 (7.8) |
| Abdominal pain | 5 (6.7) | 2 (4.9) | 7 (6.0) |
| Upper abdominal pain | 4 (5.3) | 3 (7.3) | 7 (6.0) |
| Anorexia | 6 (8.0) | 1 (2.4) | 7 (6.0) |
| . | < 20 mg/kg/d (n = 75), no. (%) . | ≥ 20-< 30 mg/kg/d (n = 41), no. (%) . | All (n = 116), no. (%) . |
|---|---|---|---|
| Nausea | 19 (25.3) | 7 (17.1) | 26 (22.4) |
| Diarrhea | 10 (13.3) | 8 (19.5) | 18 (15.5) |
| Rash | 9 (12.0) | 4 (9.8) | 13 (11.2) |
| Vomiting | 9 (12.0) | 1 (2.4) | 10 (8.6) |
| Dyspepsia | 8 (10.7) | 1 (2.4) | 9 (7.8) |
| Abdominal pain | 5 (6.7) | 2 (4.9) | 7 (6.0) |
| Upper abdominal pain | 4 (5.3) | 3 (7.3) | 7 (6.0) |
| Anorexia | 6 (8.0) | 1 (2.4) | 7 (6.0) |