Table 1

Drug doses and schedules

DoseRouteDay
Pretreatment (1 wk)    
    Vincristine 1 mg IV −6 
    Prednisone 100 mg PO −6-0 
BACOPP (recycle day 22)    
    Cyclophosphamide 650 mg/m2 IV 
    Adriamycin 50 mg/m2 IV 
    Procarbazine 100 mg/m2 PO 1-7 
    Prednisone 40 mg/m2 PO 1-14 
    Bleomycin 10 mg/m2 IV 
    Vincristine 1.4 mg/m2* IV 
DoseRouteDay
Pretreatment (1 wk)    
    Vincristine 1 mg IV −6 
    Prednisone 100 mg PO −6-0 
BACOPP (recycle day 22)    
    Cyclophosphamide 650 mg/m2 IV 
    Adriamycin 50 mg/m2 IV 
    Procarbazine 100 mg/m2 PO 1-7 
    Prednisone 40 mg/m2 PO 1-14 
    Bleomycin 10 mg/m2 IV 
    Vincristine 1.4 mg/m2* IV 

BACOPP indicates bleomycin, Adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone; IV, intravenous; and PO, per os.

*

Patients younger than 65 years receive a maximum of 2 mg; patients older than 65 years receive a maximum of 1 mg.

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