Drug doses and schedules
. | Dose . | Route . | Day . |
---|---|---|---|
Pretreatment (1 wk) | |||
Vincristine | 1 mg | IV | −6 |
Prednisone | 100 mg | PO | −6-0 |
BACOPP (recycle day 22) | |||
Cyclophosphamide | 650 mg/m2 | IV | 1 |
Adriamycin | 50 mg/m2 | IV | 1 |
Procarbazine | 100 mg/m2 | PO | 1-7 |
Prednisone | 40 mg/m2 | PO | 1-14 |
Bleomycin | 10 mg/m2 | IV | 8 |
Vincristine | 1.4 mg/m2* | IV | 8 |
. | Dose . | Route . | Day . |
---|---|---|---|
Pretreatment (1 wk) | |||
Vincristine | 1 mg | IV | −6 |
Prednisone | 100 mg | PO | −6-0 |
BACOPP (recycle day 22) | |||
Cyclophosphamide | 650 mg/m2 | IV | 1 |
Adriamycin | 50 mg/m2 | IV | 1 |
Procarbazine | 100 mg/m2 | PO | 1-7 |
Prednisone | 40 mg/m2 | PO | 1-14 |
Bleomycin | 10 mg/m2 | IV | 8 |
Vincristine | 1.4 mg/m2* | IV | 8 |
BACOPP indicates bleomycin, Adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone; IV, intravenous; and PO, per os.
Patients younger than 65 years receive a maximum of 2 mg; patients older than 65 years receive a maximum of 1 mg.