Overview about pEFS at 5 years, according to position of mutations
| Position of mutation . | Number of patients with the respective mutation . | pEFS at 5 years . |
|---|---|---|
| Only in HD domain | 27 | 92% ± 5% |
| Only in PEST domain | 11 | 76% ± 15% |
| Only in HD + PEST domain | 14 | 85% ± 10% |
| Only in FBXW7 | 4 | 75% ± 22% |
| Only in HD + FBXW7 | 15 | 76% ± 12% |
| Position of mutation . | Number of patients with the respective mutation . | pEFS at 5 years . |
|---|---|---|
| Only in HD domain | 27 | 92% ± 5% |
| Only in PEST domain | 11 | 76% ± 15% |
| Only in HD + PEST domain | 14 | 85% ± 10% |
| Only in FBXW7 | 4 | 75% ± 22% |
| Only in HD + FBXW7 | 15 | 76% ± 12% |
P(Log-Rank) = .89; not considered for calculation are 1 case with a single mutation in TAD, 1 case with mutations in TAD and FBXW7, and 1 case with mutations in HD, PEST domain, and FBXW7.