Table 1 Classification of CISs... | American Society of Hematology

Table 1

Classification of CISs identified in Runx1^+/+ and Runx1^−/− mice

Classification of CIS/chromosome number*	Gene†	Runx1^+/+, n = 52	Runx1^−/−, n = 63
Known CISs, n = 16
5	Gfi1/Evi5‡	2	11 (1)§, (3)∥
15	c-Myc‡	3	11
17	Ccnd3‡	2	6
7	RRas2	4	5
10	Ahi1/Myb	7 (1)¶	3 (2)#
2	Rasgrp1	2	2
11	Ikaros**	1	2
3	Evi1‡	0	5
6	Ccnd2‡	0	3
12	N-myc‡,**	0	3
17	Pim1	0	3
2	Bcas1	0	2
5	Bcl7a	0	2
5	Mad1l1**	0	2
7	Sema4b	0	2
12	Jundm2	0	2
Novel CIS, n = 4
X	Slis6	0	4
3	Slis7	0	3
5	Slis8	0	2
16	Slis9	0	2

Classification of CIS/chromosome number*	Gene†	Runx1^+/+, n = 52	Runx1^−/−, n = 63
Known CISs, n = 16
5	Gfi1/Evi5‡	2	11 (1)§, (3)∥
15	c-Myc‡	3	11
17	Ccnd3‡	2	6
7	RRas2	4	5
10	Ahi1/Myb	7 (1)¶	3 (2)#
2	Rasgrp1	2	2
11	Ikaros**	1	2
3	Evi1‡	0	5
6	Ccnd2‡	0	3
12	N-myc‡,**	0	3
17	Pim1	0	3
2	Bcas1	0	2
5	Bcl7a	0	2
5	Mad1l1**	0	2
7	Sema4b	0	2
12	Jundm2	0	2
Novel CIS, n = 4
X	Slis6	0	4
3	Slis7	0	3
5	Slis8	0	2
16	Slis9	0	2

CIS indicates common integration site; and RIS, retroviral integration site.

The genomic positions of the RIS were determined according to BLAT search of the UCSC Genome Bioinformatics database.

Candidate genes in the vicinity of the RIS are shown.

CISs that are particularly interesting and are discussed in the text.

Number in parentheses indicates number of integrations inside Gfi1.

Number in parentheses indicates number of integrations inside Evi5.

Number in parentheses indicates number of integrations inside Myb.

Number in parentheses indicates number of integrations inside Ahi1.

Genes with all retroviral integrations inside the gene.