Summary of potentially related cases in the literature
| Reference . | Age at presentation, y/sex . | Infections . | Cytopenias . | Clinical features . | Outcome . |
|---|---|---|---|---|---|
| Ballas et al19 | 23/female (sister with acute leukemia; mother with genital cancer who died of progressive sarcoidosis) | Genital and periungual HPV | Monocytes, B cells, NK cells | Lymphadenitis, diffuse pulmonary disease | Not reported |
| Couderc et al20,21 | 32/female | Genital HPV, buccal herpes simplex virus, disseminated MAC | Neutrophils (mild), monocytes, lymphocytes | Pulmonary alveolar proteinosis | Died of respiratory failure |
| Wendland et al22 | 15/male | Salmonella enteritis, disseminated MAC, disseminated VZV | Monocytes, B cells, NK cells, T cells | Died of VZV-related multiorgan failure | |
| Khanjari et al23 | 19/male | Disseminated MAC | “idiopathic marrow aplasia,” monocytes, T cells | Pulmonary alveolar proteinosis | Not reported |
| Witzke et al24 | 38/female | Widespread vulvar HPV | Monocytes, B cells, NK cells | Pulmonary alveolar proteinosis, membranous nephropathy | Died of respiratory failure |
| Kobashi et al25 | 14/male | Pulmonary MAC | Monocytes, lymphocytes, platelets | Not reported | |
| Kobashi et al25 | 19/male (brother) | Disseminated MAC (age 22) | MDS (age 17) | Not reported |
| Reference . | Age at presentation, y/sex . | Infections . | Cytopenias . | Clinical features . | Outcome . |
|---|---|---|---|---|---|
| Ballas et al19 | 23/female (sister with acute leukemia; mother with genital cancer who died of progressive sarcoidosis) | Genital and periungual HPV | Monocytes, B cells, NK cells | Lymphadenitis, diffuse pulmonary disease | Not reported |
| Couderc et al20,21 | 32/female | Genital HPV, buccal herpes simplex virus, disseminated MAC | Neutrophils (mild), monocytes, lymphocytes | Pulmonary alveolar proteinosis | Died of respiratory failure |
| Wendland et al22 | 15/male | Salmonella enteritis, disseminated MAC, disseminated VZV | Monocytes, B cells, NK cells, T cells | Died of VZV-related multiorgan failure | |
| Khanjari et al23 | 19/male | Disseminated MAC | “idiopathic marrow aplasia,” monocytes, T cells | Pulmonary alveolar proteinosis | Not reported |
| Witzke et al24 | 38/female | Widespread vulvar HPV | Monocytes, B cells, NK cells | Pulmonary alveolar proteinosis, membranous nephropathy | Died of respiratory failure |
| Kobashi et al25 | 14/male | Pulmonary MAC | Monocytes, lymphocytes, platelets | Not reported | |
| Kobashi et al25 | 19/male (brother) | Disseminated MAC (age 22) | MDS (age 17) | Not reported |