Table 3

The influence of factor VIII:C, hypertension, and smoking on the risk of arterial thrombosis in 195 multiple myeloma patients

Risk factorUnivariate analysis, HR (95% CI)Multivariate analysis,* HR (95% CI)
Factor VIII:C† 1.92 (1.17-3.14) 1.85 (0.99-3.47) 
Hypertension 3.70 (1.13-12.2) 11.7 (2.23-61.2) 
Smoking 6.25 (1.61-24.2) 15.2 (1.78-130) 
Risk factorUnivariate analysis, HR (95% CI)Multivariate analysis,* HR (95% CI)
Factor VIII:C† 1.92 (1.17-3.14) 1.85 (0.99-3.47) 
Hypertension 3.70 (1.13-12.2) 11.7 (2.23-61.2) 
Smoking 6.25 (1.61-24.2) 15.2 (1.78-130) 

HR indicates hazard ratio; and CI, confidence interval.

*

Adjusted for age, ISS score, and assigned treatment arm.

†

For each IU/mL increase in FVIII level.

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