Patient characteristics
HCT patient characteristics . | n = 120 . |
---|---|
Median patient age, y (range) | 49 (19-66) |
Median donor age, y (range) | 48 (15-74) |
Primary disease | |
Acute lymphoblastic leukemia | 9 (8%) |
Acute myelogenous leukemia | 37 (31%) |
Chronic lymphocytic leukemia | 8 (7%) |
Chronic myelogenous leukemia | 10 (8%) |
Hodgkin disease | 2 (1%) |
Myelodysplastic syndrome | 8 (7%) |
Myelofibrosis | 3 (2%) |
Multiple myeloma | 18 (15%) |
Mantle cell lymphoma | 8 (7%) |
Non-Hodgkin lymphoma | 13 (11%) |
Severe aplastic anemia | 4 (3%) |
Conditioning | |
Myeloablative | 52 (43%) |
Nonmyeloablative | 68 (57%) |
Donor | |
Related–HLA identical | 92 (77%) |
Unrelated–HLA identical | 25 (21%) |
Unrelated–HLA mismatch | 3 (2%) |
Graft | |
Bone marrow | 8 (7%) |
Peripheral blood stem cell | 112 (93%) |
HCT patient characteristics . | n = 120 . |
---|---|
Median patient age, y (range) | 49 (19-66) |
Median donor age, y (range) | 48 (15-74) |
Primary disease | |
Acute lymphoblastic leukemia | 9 (8%) |
Acute myelogenous leukemia | 37 (31%) |
Chronic lymphocytic leukemia | 8 (7%) |
Chronic myelogenous leukemia | 10 (8%) |
Hodgkin disease | 2 (1%) |
Myelodysplastic syndrome | 8 (7%) |
Myelofibrosis | 3 (2%) |
Multiple myeloma | 18 (15%) |
Mantle cell lymphoma | 8 (7%) |
Non-Hodgkin lymphoma | 13 (11%) |
Severe aplastic anemia | 4 (3%) |
Conditioning | |
Myeloablative | 52 (43%) |
Nonmyeloablative | 68 (57%) |
Donor | |
Related–HLA identical | 92 (77%) |
Unrelated–HLA identical | 25 (21%) |
Unrelated–HLA mismatch | 3 (2%) |
Graft | |
Bone marrow | 8 (7%) |
Peripheral blood stem cell | 112 (93%) |
Patient characteristics of 120 patients with various leukemic diseases are described. These patients were screened for NuSAP1 and CHAF1b antibodies using quantitative IgG ELISA.