Percentages of cells in the different splenic and bone marrow erythroblast populations
| . | ERK1+/+ . | ERK1−/− . | P . |
|---|---|---|---|
| Spleen* | |||
| Ter119+ cells | 37.24 ± 2.24 | 43.58 ± 1.85 | .038† |
| ProE population | 0.12 ± 0.02 | 0.36 ± 0.05 | < .001† |
| Ery.A population | 7.01 ± 0.55 | 19.08 ± 1.18 | < .001† |
| Ery.B population | 9.42 ± 1.00 | 14.28 ± 1.03 | .005† |
| Ery.C population | 83.31 ± 1.32 | 66.27 ± 1.68 | < .001† |
| Bone marrow‡ | |||
| Ter119+ cells | 46.44 ± 1.68 | 46.56 ± 2.77 | NS |
| ProE population | 0.69 ± 0.04 | 0.70 ± 0.04 | NS |
| Ery.A population | 28.56 ± 1.90 | 27.78 ± 0.97 | NS |
| Ery.B population | 50.89 ± 1.84 | 50.11 ± 2.05 | NS |
| Ery.C population | 19.67 ± 1.01 | 21.44 ± 2.50 | NS |
| . | ERK1+/+ . | ERK1−/− . | P . |
|---|---|---|---|
| Spleen* | |||
| Ter119+ cells | 37.24 ± 2.24 | 43.58 ± 1.85 | .038† |
| ProE population | 0.12 ± 0.02 | 0.36 ± 0.05 | < .001† |
| Ery.A population | 7.01 ± 0.55 | 19.08 ± 1.18 | < .001† |
| Ery.B population | 9.42 ± 1.00 | 14.28 ± 1.03 | .005† |
| Ery.C population | 83.31 ± 1.32 | 66.27 ± 1.68 | < .001† |
| Bone marrow‡ | |||
| Ter119+ cells | 46.44 ± 1.68 | 46.56 ± 2.77 | NS |
| ProE population | 0.69 ± 0.04 | 0.70 ± 0.04 | NS |
| Ery.A population | 28.56 ± 1.90 | 27.78 ± 0.97 | NS |
| Ery.B population | 50.89 ± 1.84 | 50.11 ± 2.05 | NS |
| Ery.C population | 19.67 ± 1.01 | 21.44 ± 2.50 | NS |
Numbers of total Ter119+ cells and of each erythroblast subset populations are calculated as depicted in Figure 3, on freshly isolated splenocytes and bone marrow cells from ERK1+/+ and ERK1−/− mice. Data are mean percentage ± SEM.
NS indicates not significant.
ERK1+/+ (n = 14); ERK1−/− (n = 23).
Significantly different from ERK1+/+ value (P < .05).
ERK1+/+ (n = 9); ERK1−/− (n = 9).