Table 2

Clinical outcome according to BAALC expression in BCR-ABL and MLL-AF4 patients

Clinical outcomeBAALC T1 (n = 94)BAALC T2 (n = 67)BAALC T3 (n = 41)P
Complete remission, no./total (%) (n = 193) 86/92 (94) 59/65 (91) 29/36 (81) .09 
Refractory disease, no./total (%) (n = 184) 1/87 (1) 4/63 (6) 5/34 (15) .009 
Overall survival at 5 y, percentage (95% CI) (n = 202)* 70 (59-81) 52 (36-67) 38 (22-54) .004 
Relapse rate, no./total (%) (n = 114) 26/53 (49) 16/36 (44) 10/25 (40) .76 
Clinical outcomeBAALC T1 (n = 94)BAALC T2 (n = 67)BAALC T3 (n = 41)P
Complete remission, no./total (%) (n = 193) 86/92 (94) 59/65 (91) 29/36 (81) .09 
Refractory disease, no./total (%) (n = 184) 1/87 (1) 4/63 (6) 5/34 (15) .009 
Overall survival at 5 y, percentage (95% CI) (n = 202)* 70 (59-81) 52 (36-67) 38 (22-54) .004 
Relapse rate, no./total (%) (n = 114) 26/53 (49) 16/36 (44) 10/25 (40) .76 
*

Patients who received SCT in CR1 were censored at the time of transplantation.

Patients who received SCT in CR1 were excluded.

P value across the 3 BAALC tertiles. Statistical significance was reached comparing BAALC T1 vs T3 (P = .047).

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