Allo-HLA reactivity of virus-specific T-cell clones
| Specificity . | Donor . | TCR Vβ . | EBV panel . | HLA trans/block . | Figure . |
|---|---|---|---|---|---|
| pp50/A1 | MBX | * | UD | ||
| pp50/A1 | MBX | 1 | |||
| pp50/A1 | MBX | 5.1 | |||
| pp50/A1 | MBX | 3 | A*1101 | A*1101 | 2B |
| pp65/A2 | MRJ | 2 | |||
| pp65/A2 | MRJ | 13 | |||
| pp65/A2 | HRN | 8 | UD | 2G | |
| pp65/A2 | HRN | 2 | |||
| pp65/A2 | AMJ | 3 | |||
| BMLF1/A2 | GFS | * | |||
| LMP2/A2 | JVW | * | |||
| FLU/A2 | FKR | 17 | B*6401 | ||
| FLU/A2 | FKR | 17 | |||
| VZV/A2 | PKN | 14 | B*5501 | B*5501 | 3A |
| VZV/A2 | PKN | * | B*5701 | B*5701 | 3B |
| VZV/A2 | PKN | 21,3 | A*0205 | A*0205 | 3C |
| EBNA3A/A3 | HRN | * | A*3101 | A*3101 | 2A |
| BRLF1/A3 | AKO | 7.1 | |||
| BRLF1/A3 | AKO | 14 | |||
| BRLF1/A3 | AKO | 17 | |||
| BRLF1/A3 | AKO | 1 | |||
| BRLF1/A3 | DVO | 7.1 | UD | ||
| BRLF1/A3 | DVO | 8 | |||
| BRLF1/A3 | DVO | 14 | UD | ||
| BRLF1/A3 | DVO | 17 | UD | ||
| BRLF1/A3 | DVO | * | |||
| BRLF1/A3 | DVO | 7.2 | A*0201 | A*0201 | 2C |
| pp65/B7 | BDV | 7.2 | |||
| pp65/B7 | BDV | 7.2 | DRB1*0801 | DRB1*0801 | 2D |
| EBNA3A/B8 | LDO | * | B*4402, B*5501 | B*4402, B*5501 | 2E |
| BZLF/B8 | AVK | 7.1 | |||
| BZLF/B8 | AVK | * | |||
| BZLF/B8 | AVK | 5.1 | |||
| pp65/B35 | MED | 3 | |||
| pp65/B35 | MED | 5.1 | DRB1*0401 | DRB1*0401 | |
| pp65/B35 | MED | * | |||
| pp65/DR1 | CBH | 2 | |||
| pp65/DR1 | CBH | * | |||
| pp65/DR1 | MSV | 8 | DRB1*0901 | ||
| pp65/DR1 | MSV | * | DRB3*0101 | DRB3*0101 | |
| FLU/DR4 | VKY | 3 | DRB1*1301 | DRB1*1301 | 2F |
| Specificity . | Donor . | TCR Vβ . | EBV panel . | HLA trans/block . | Figure . |
|---|---|---|---|---|---|
| pp50/A1 | MBX | * | UD | ||
| pp50/A1 | MBX | 1 | |||
| pp50/A1 | MBX | 5.1 | |||
| pp50/A1 | MBX | 3 | A*1101 | A*1101 | 2B |
| pp65/A2 | MRJ | 2 | |||
| pp65/A2 | MRJ | 13 | |||
| pp65/A2 | HRN | 8 | UD | 2G | |
| pp65/A2 | HRN | 2 | |||
| pp65/A2 | AMJ | 3 | |||
| BMLF1/A2 | GFS | * | |||
| LMP2/A2 | JVW | * | |||
| FLU/A2 | FKR | 17 | B*6401 | ||
| FLU/A2 | FKR | 17 | |||
| VZV/A2 | PKN | 14 | B*5501 | B*5501 | 3A |
| VZV/A2 | PKN | * | B*5701 | B*5701 | 3B |
| VZV/A2 | PKN | 21,3 | A*0205 | A*0205 | 3C |
| EBNA3A/A3 | HRN | * | A*3101 | A*3101 | 2A |
| BRLF1/A3 | AKO | 7.1 | |||
| BRLF1/A3 | AKO | 14 | |||
| BRLF1/A3 | AKO | 17 | |||
| BRLF1/A3 | AKO | 1 | |||
| BRLF1/A3 | DVO | 7.1 | UD | ||
| BRLF1/A3 | DVO | 8 | |||
| BRLF1/A3 | DVO | 14 | UD | ||
| BRLF1/A3 | DVO | 17 | UD | ||
| BRLF1/A3 | DVO | * | |||
| BRLF1/A3 | DVO | 7.2 | A*0201 | A*0201 | 2C |
| pp65/B7 | BDV | 7.2 | |||
| pp65/B7 | BDV | 7.2 | DRB1*0801 | DRB1*0801 | 2D |
| EBNA3A/B8 | LDO | * | B*4402, B*5501 | B*4402, B*5501 | 2E |
| BZLF/B8 | AVK | 7.1 | |||
| BZLF/B8 | AVK | * | |||
| BZLF/B8 | AVK | 5.1 | |||
| pp65/B35 | MED | 3 | |||
| pp65/B35 | MED | 5.1 | DRB1*0401 | DRB1*0401 | |
| pp65/B35 | MED | * | |||
| pp65/DR1 | CBH | 2 | |||
| pp65/DR1 | CBH | * | |||
| pp65/DR1 | MSV | 8 | DRB1*0901 | ||
| pp65/DR1 | MSV | * | DRB3*0101 | DRB3*0101 | |
| FLU/DR4 | VKY | 3 | DRB1*1301 | DRB1*1301 | 2F |
TCR indicates T-cell receptor; and UD, undetermined allo-HLA reactivity, which could not be characterized because the recognized EBV-LCLs did not share one particular allo-HLA molecule.
The TCR Vβ of the clone could not be determined with the TCR Vβ kit.