Table 4

Multivariate data regression (analysis of maximum likelihood estimates) of EFS (n = 318 NPM1-mutated AML cases)

VariablePr > χ2 testHazard ratio (95% confidence limits)
Age as continuous variable 0.1697 1.010 (0.996-1.025) 
FLT3: Mutated vs unmutated 0.0161 1.597 (1.091-2.337) 
Karyotype: aberrant vs normal 0.1335 1.482 (0.886-2.479) 
MLD: positive vs negative 0.4084 0.827 (0.526-1.298) 
VariablePr > χ2 testHazard ratio (95% confidence limits)
Age as continuous variable 0.1697 1.010 (0.996-1.025) 
FLT3: Mutated vs unmutated 0.0161 1.597 (1.091-2.337) 
Karyotype: aberrant vs normal 0.1335 1.482 (0.886-2.479) 
MLD: positive vs negative 0.4084 0.827 (0.526-1.298) 

EFS indicates event-free survival; AML, acute myeloid leukemia; Pr, probability; and MLD, multilineage dysplasia.

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