Double ASCT versus ASCT/Allo-RIC
| Reference . | No. of patients . | CR rate, % . | EFS, mo . | OS, mo . |
|---|---|---|---|---|
| Garban et al98 (2006) | 166 vs 51 | 32.5 vs 32.6 | 31.7 vs 35 | 42.7 vs 35 |
| P | NS | NS | .07 | |
| Bruno et al99 (2007) | 82 vs 80 | 26 vs 55 | 29 vs 35 | 54 vs 80 |
| P | .004 | .02 | .01 | |
| Rosiñol et al100 (2008) | 85 vs 25 | 11 vs 40%* | 26 vs 19.6 | 58 vs NR |
| P | .01 | NS | NS |
| Reference . | No. of patients . | CR rate, % . | EFS, mo . | OS, mo . |
|---|---|---|---|---|
| Garban et al98 (2006) | 166 vs 51 | 32.5 vs 32.6 | 31.7 vs 35 | 42.7 vs 35 |
| P | NS | NS | .07 | |
| Bruno et al99 (2007) | 82 vs 80 | 26 vs 55 | 29 vs 35 | 54 vs 80 |
| P | .004 | .02 | .01 | |
| Rosiñol et al100 (2008) | 85 vs 25 | 11 vs 40%* | 26 vs 19.6 | 58 vs NR |
| P | .01 | NS | NS |
ASCT indicates autologous stem cell transplantation; allo-RIC, reduced-intensity conditioning allogeneic transplantation; CR, complete remission; EFS, event-free survival; OS, overall survival; NS, not significant; and NR, not reached.
Response improvement with second transplantation.