Myeloablative versus RIC allogeneic transplantation
| Procedure . | No. of patients . | TRM, % . | CR rate, % . | PFS, % at 3 y . | OS, % at 3 y . |
|---|---|---|---|---|---|
| Myeloablative | 196 | 37 | 53.4 | 18.9 | 50.8 |
| RIC | 320 | 24 | 33.6 | 34.5 | 38.1 |
| P | .002 | < .001 | < .001 | NS |
| Procedure . | No. of patients . | TRM, % . | CR rate, % . | PFS, % at 3 y . | OS, % at 3 y . |
|---|---|---|---|---|---|
| Myeloablative | 196 | 37 | 53.4 | 18.9 | 50.8 |
| RIC | 320 | 24 | 33.6 | 34.5 | 38.1 |
| P | .002 | < .001 | < .001 | NS |
Data are from the European Group for Blood and Marrow Transplantation experience, 1998 to 2002.7
RIC indicates reduced intensity conditioning; TRM, transplantation-related mortality; CR, complete remission; OS, overall survival; PFS, progression-free survival; and NS, not significant.