Characteristics of MGUS and/or MM in 55 relative pairs*
| Proband characteristic . | . | First-degree relative characteristic . | . | P† . | |
|---|---|---|---|---|---|
| Age, y | <65 | ≥65 | .56 | ||
| Younger than 65 | 9 (31.0) | 20 (69.0) | |||
| 65 or older | 10 (38.5) | 16 (61.5) | |||
| Sex | Female | Male | . | .58 | |
| Female | 14 (56.0) | 11 (44.0) | |||
| Male | 19 (63.3) | 11 (36.7) | |||
| Monoclonal protein concentration, g/dL | <1.5 | ≥1.5 | .25 | ||
| Less than 1.5 | 16 (88.9) | 2 (11.1) | |||
| 1.5 or more | 36 (97.3) | 1 (2.7) | |||
| Monoclonal immunoglobulin isotype | IgG | IgA | IgM | Light chain only | .23 |
| IgG | 32 (84.2) | 2 (5.3) | 2 (5.3) | 2 (5.3) | |
| IgA | 6 (66.7) | 1 (11.1) | 1 (11.1) | 1 (11.1) | |
| IgM | 1 (33.3) | 1 (33.3) | 1 (33.3) | 0 (0) | |
| Light chain only | 1 (100) | 0 (0) | 0 (0) | 0 (0) | |
| Proband characteristic . | . | First-degree relative characteristic . | . | P† . | |
|---|---|---|---|---|---|
| Age, y | <65 | ≥65 | .56 | ||
| Younger than 65 | 9 (31.0) | 20 (69.0) | |||
| 65 or older | 10 (38.5) | 16 (61.5) | |||
| Sex | Female | Male | . | .58 | |
| Female | 14 (56.0) | 11 (44.0) | |||
| Male | 19 (63.3) | 11 (36.7) | |||
| Monoclonal protein concentration, g/dL | <1.5 | ≥1.5 | .25 | ||
| Less than 1.5 | 16 (88.9) | 2 (11.1) | |||
| 1.5 or more | 36 (97.3) | 1 (2.7) | |||
| Monoclonal immunoglobulin isotype | IgG | IgA | IgM | Light chain only | .23 |
| IgG | 32 (84.2) | 2 (5.3) | 2 (5.3) | 2 (5.3) | |
| IgA | 6 (66.7) | 1 (11.1) | 1 (11.1) | 1 (11.1) | |
| IgM | 1 (33.3) | 1 (33.3) | 1 (33.3) | 0 (0) | |
| Light chain only | 1 (100) | 0 (0) | 0 (0) | 0 (0) | |