Table 4

Baseline characteristics of patients with complete response

CharacteristicProportion of tipifarnib patients with CR (%)
Age, y  
    Less than 75 7/92 (8) 
    75 or more 11/136 (8) 
AML with myelodysplasia  
    Yes 8/90 (9) 
    No 10/138 (7) 
Unfavorable cytogenetics  
    Yes 3/68 (4) 
    No 12/123 (10) 
    Not done 3/37 (8) 
ECOG performance status  
    0 5/46 (11) 
    1 9/119 (8) 
    2 4/63 (6) 
Baseline blasts in marrow, range 21%-98% 
CharacteristicProportion of tipifarnib patients with CR (%)
Age, y  
    Less than 75 7/92 (8) 
    75 or more 11/136 (8) 
AML with myelodysplasia  
    Yes 8/90 (9) 
    No 10/138 (7) 
Unfavorable cytogenetics  
    Yes 3/68 (4) 
    No 12/123 (10) 
    Not done 3/37 (8) 
ECOG performance status  
    0 5/46 (11) 
    1 9/119 (8) 
    2 4/63 (6) 
Baseline blasts in marrow, range 21%-98% 

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