Multivariate analysis of risk factors after reduced-intensity conditioning and allogeneic stem cell transplantation for patients with myelofibrosis
. | Overall survival, HR (95% CI) . | P . | Disease-free survival, HR (95% CI) . | P . | Relapse, HR (95% CI) . | P . |
---|---|---|---|---|---|---|
Age | ||||||
Less than or equal to 55 y | 1.0 | .02 | — | — | ||
More than 55 y | 2.70 (1.21-6.03) | — | — | |||
HLA | ||||||
Match | 1.0 | .006 | 1.0 | .01 | — | |
Mismatched | 3.04 (1.38-6.65) | 2.39 (1.22-4.69) | — | |||
Lille score | ||||||
Low | — | 1.0 | .02 | 1.0 | .03 | |
Intermediate | — | 3.10 (0.91-10.58) | .07 | 1.94 (0.42-9.02) | .40 | |
High | — | 5.37 (1.58-18.24) | .007 | 5.23 (1.14-24.01) | .03 | |
Splenectomy | ||||||
No | — | — | 1.0 | .006 | ||
Yes | — | — | 3.58 (1.44-8.86) |
. | Overall survival, HR (95% CI) . | P . | Disease-free survival, HR (95% CI) . | P . | Relapse, HR (95% CI) . | P . |
---|---|---|---|---|---|---|
Age | ||||||
Less than or equal to 55 y | 1.0 | .02 | — | — | ||
More than 55 y | 2.70 (1.21-6.03) | — | — | |||
HLA | ||||||
Match | 1.0 | .006 | 1.0 | .01 | — | |
Mismatched | 3.04 (1.38-6.65) | 2.39 (1.22-4.69) | — | |||
Lille score | ||||||
Low | — | 1.0 | .02 | 1.0 | .03 | |
Intermediate | — | 3.10 (0.91-10.58) | .07 | 1.94 (0.42-9.02) | .40 | |
High | — | 5.37 (1.58-18.24) | .007 | 5.23 (1.14-24.01) | .03 | |
Splenectomy | ||||||
No | — | — | 1.0 | .006 | ||
Yes | — | — | 3.58 (1.44-8.86) |
— indicates not applicable.