Distribution of I-FISH data according to CBA data
Cytogenetic response by CBA . | Cytogenetic response by I-FISH, n (%) . | ||
---|---|---|---|
Less than 1% BCR-ABL+ nuclei . | 1%-5% BCR-ABL+ nuclei . | More than 5% BCR-ABL+ nuclei . | |
CCgR (n = 537), no Ph+ metaphases | 444 (82.7) | 71(13.2) | 22 (4.1) |
PCgR (n = 77), 1%-35% Ph+ metaphases | 7 (9.1) | 32 (41.6) | 38 (49.3) |
P | < .001 | < .001 | < .001 |
Cytogenetic response by CBA . | Cytogenetic response by I-FISH, n (%) . | ||
---|---|---|---|
Less than 1% BCR-ABL+ nuclei . | 1%-5% BCR-ABL+ nuclei . | More than 5% BCR-ABL+ nuclei . | |
CCgR (n = 537), no Ph+ metaphases | 444 (82.7) | 71(13.2) | 22 (4.1) |
PCgR (n = 77), 1%-35% Ph+ metaphases | 7 (9.1) | 32 (41.6) | 38 (49.3) |
P | < .001 | < .001 | < .001 |
CBA indicates chromosome banding analysis; CCgR, complete cytogenetic response; I-FISH, interphase fluorescence in situ hybridization; and PCgR, partial cytogenetic response.