GOstat functional analysis of miRNA targets for miRNAs that are increased upon MDDC differentiation
| GO ID . | Functional group . | Count . | Targets . | miRNAs predicted to target these genes . | Total . | P . |
|---|---|---|---|---|---|---|
| Biologic process | ||||||
| Development | ||||||
| Organ development | ||||||
| GO:0048637 | Skeletal muscle development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0048747 | Muscle fiber development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0048741 | Skeletal muscle fiber development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0009790 | Embryonic development | 3 | MBNL1; KIF1B; FUT 8 | miR-21, 99b, 125a, 7e, 34a, 342 | 92 | .007 |
| GO:0009792 | Embryonic development (sensu Metazoa) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 27 | .035 |
| GO:0043009 | Embryonic development (sensu Vertebrata) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 12 | .011 |
| GO:0001701 | Embryonic development (sensu Mammalia) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 11 | .010 |
| Cellular process | ||||||
| GO:0051865 | Protein autoubiquitination; cell differentiation | 1 | UHRF2 | miR-34a, 7e | 1 | .031 |
| GO:0045445 | Myoblast differentiation | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 16 | .018 |
| GO:0045165 | Cell fate commitment | 2 | WNT 1; JAG1 | miR-21, 34a, 7e | 20 | .025 |
| Molecular function | ||||||
| Enzyme regulator activity | ||||||
| Enzyme activator activity | ||||||
| GO:0005099 | Ras GTPase activator activity; catalytic activity | 1 | RASAL2 | miR-342, 125a | 12 | .011 |
| GO:0046921 | α(1,6)-fucosyltransferase activity | 1 | FUT 8 | miR-34a, 342 | 1 | .031 |
| GO:0008424 | Glycoprotein 6-alpha-L-fucosyltransferase activity | 1 | FUT 8 | miR-34a, 342 | 1 | .031 |
| Binding | ||||||
| GO:0051018 | Protein kinase A binding | 1 | AKAP6 | miR-34a, 7e | 11 | .010 |
| GO:0051020 | GTPase binding | 2 | DOCK3; MYRIP | miR-125a, 7e, 34a | 92 | .035 |
| GO ID . | Functional group . | Count . | Targets . | miRNAs predicted to target these genes . | Total . | P . |
|---|---|---|---|---|---|---|
| Biologic process | ||||||
| Development | ||||||
| Organ development | ||||||
| GO:0048637 | Skeletal muscle development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0048747 | Muscle fiber development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0048741 | Skeletal muscle fiber development | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 21 | .025 |
| GO:0009790 | Embryonic development | 3 | MBNL1; KIF1B; FUT 8 | miR-21, 99b, 125a, 7e, 34a, 342 | 92 | .007 |
| GO:0009792 | Embryonic development (sensu Metazoa) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 27 | .035 |
| GO:0043009 | Embryonic development (sensu Vertebrata) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 12 | .011 |
| GO:0001701 | Embryonic development (sensu Mammalia) | 2 | MBNL1; FUT 8 | miR-21, 99b, 34a, 342 | 11 | .010 |
| Cellular process | ||||||
| GO:0051865 | Protein autoubiquitination; cell differentiation | 1 | UHRF2 | miR-34a, 7e | 1 | .031 |
| GO:0045445 | Myoblast differentiation | 2 | JAG1; MBNL1 | miR-21, 34a, 99b | 16 | .018 |
| GO:0045165 | Cell fate commitment | 2 | WNT 1; JAG1 | miR-21, 34a, 7e | 20 | .025 |
| Molecular function | ||||||
| Enzyme regulator activity | ||||||
| Enzyme activator activity | ||||||
| GO:0005099 | Ras GTPase activator activity; catalytic activity | 1 | RASAL2 | miR-342, 125a | 12 | .011 |
| GO:0046921 | α(1,6)-fucosyltransferase activity | 1 | FUT 8 | miR-34a, 342 | 1 | .031 |
| GO:0008424 | Glycoprotein 6-alpha-L-fucosyltransferase activity | 1 | FUT 8 | miR-34a, 342 | 1 | .031 |
| Binding | ||||||
| GO:0051018 | Protein kinase A binding | 1 | AKAP6 | miR-34a, 7e | 11 | .010 |
| GO:0051020 | GTPase binding | 2 | DOCK3; MYRIP | miR-125a, 7e, 34a | 92 | .035 |