Table 6

Multiple linear regression models incorporating VTE patients

ParameterCoefficient (95% confidence interval)Contribution to variance, percentageP
Clot permeability as dependent variable    
    Final model  22.8 < .001 
    Fibrinogen −0.17 (−0.28 to −0.09) 6.3 < .001 
    D-dimer −0.13 (−0.22 to −0.05) 4.8 < .001 
    Age −0.11 (−0.18 to −0.03) 2.8 < .05 
    CRP −1.22 (−2.35 to −0.18) 2.5 < .05 
    tPA −0.09 (−0.14 to 0.03) 0.7 NS 
    PAI-1 0.21 (−0.24 to 0.57) 0.5 NS 
Lysis time t50% as dependent variable    
    Final model  23.1 < .001 
    Fibrinogen 0.76 (0.55 to 0.92) 6.2 < .001 
    D-dimer 0.61 (0.3 to 1.02) 4.4 < .001 
    PAI-1 0.17 (0.05 to 0.26) 3.5 < .001 
    CRP 0.08 (0.03 to 0.13) 1.7 < .05 
    tPA 0.22 (−0.03 to 0.2) 0.8 NS 
    Age 0.03 (−0.03 to 0.14) 0.5 NS 
ParameterCoefficient (95% confidence interval)Contribution to variance, percentageP
Clot permeability as dependent variable    
    Final model  22.8 < .001 
    Fibrinogen −0.17 (−0.28 to −0.09) 6.3 < .001 
    D-dimer −0.13 (−0.22 to −0.05) 4.8 < .001 
    Age −0.11 (−0.18 to −0.03) 2.8 < .05 
    CRP −1.22 (−2.35 to −0.18) 2.5 < .05 
    tPA −0.09 (−0.14 to 0.03) 0.7 NS 
    PAI-1 0.21 (−0.24 to 0.57) 0.5 NS 
Lysis time t50% as dependent variable    
    Final model  23.1 < .001 
    Fibrinogen 0.76 (0.55 to 0.92) 6.2 < .001 
    D-dimer 0.61 (0.3 to 1.02) 4.4 < .001 
    PAI-1 0.17 (0.05 to 0.26) 3.5 < .001 
    CRP 0.08 (0.03 to 0.13) 1.7 < .05 
    tPA 0.22 (−0.03 to 0.2) 0.8 NS 
    Age 0.03 (−0.03 to 0.14) 0.5 NS 

NS indicates not significant. See Table 1 for other abbreviations.

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