Table 6 Clinical and complement data in... | American Society of Hematology

Table 6

Clinical and complement data in patients with aHUS with anti-fH autoantibodies

Patient	HUS onset			First serum sample analyzed					Current age and situation
Patient	Age, y	Plasma therapy	Renal function	Time after onset	AutoAb titer, AU/mL*	C3, mg/dL*	C4, mg/dL*	CFH, mg/dL*	Current age and situation
H87	5	PE	Full recovery	Onset	600	55.7†	8.85†	25	11 y; unknown
H108	4	PE	Full recovery	3 mo	1600	86.2	28.4	22	8 y; ESRD
H119	4	None	ESRD	13 y	600	117	16.6	28	20 y; RT since 1995
H151	6	PE + PI	Full recovery	7 mo	6000	66.7†	16.7	31	8 y; stable with corticoids
H154	8	PE	Full recovery	Onset	18 000	58.5†	19.6	26	10 y; stable with azathioprine
H171	3	None	ESRD	5 mo	3600	81.3	40.6	25	4 y; RT since March 2009
H177	7	PF + 5% albumin	Death (myocarditis)	Onset	16 000	58.5†	19.6	22	Died during first episode

Patient	HUS onset			First serum sample analyzed					Current age and situation
Patient	Age, y	Plasma therapy	Renal function	Time after onset	AutoAb titer, AU/mL*	C3, mg/dL*	C4, mg/dL*	CFH, mg/dL*	Current age and situation
H87	5	PE	Full recovery	Onset	600	55.7†	8.85†	25	11 y; unknown
H108	4	PE	Full recovery	3 mo	1600	86.2	28.4	22	8 y; ESRD
H119	4	None	ESRD	13 y	600	117	16.6	28	20 y; RT since 1995
H151	6	PE + PI	Full recovery	7 mo	6000	66.7†	16.7	31	8 y; stable with corticoids
H154	8	PE	Full recovery	Onset	18 000	58.5†	19.6	26	10 y; stable with azathioprine
H171	3	None	ESRD	5 mo	3600	81.3	40.6	25	4 y; RT since March 2009
H177	7	PF + 5% albumin	Death (myocarditis)	Onset	16 000	58.5†	19.6	22	Died during first episode

PE indicates plasma exchange; PF, plasmapheresis; PI, plasma infusion; ESRD, end-stage renal disease; and RT, renal transplant.

Normal values: AutoAb titer, < 150 AU/mL; C3, 77-135 mg/dL; C4, 14-47 mg/dL; CFH, 12-56 mg/dL.

Value out of normal range.