Genetic, molecular, and clinical data of patients with 17p deletion
| Subgroup/patient no. . | 17p del (% positive cells) . | 13q del (% positive cells) . | IGHV % homology . | ZAP-70+ cells, % . | TTT, mos . | Therapy . |
|---|---|---|---|---|---|---|
| 17p aggressive | ||||||
| 16 | 84.0 | 52.0 | 99.3 | 50.2 | 0 | Yes |
| 17 | 86.0 | 49.5 | 99.6 | 76.8 | 0 | Yes |
| 100 | 7.5 | 59.0 | 88.4 | 3.8 | 24 | Yes |
| 20 | 96.0 | 0.0 | 99.6 | 36.4 | 0 | Yes |
| 21 | 76.0 | 70.0 | 99.3 | 36.5 | 0 | Yes |
| 22 | 93.0 | 94.5 | 99.6 | 84.8 | 0 | Yes |
| 23 | 61.0 | 15.0 | 99.3 | 42.6 | 0.5 | Yes |
| 24 | 69.5 | 70.0 | 99.6 | 53.7 | 6 | Yes |
| 114 | 9.0 | 40.0 | 90.6 | 6.0 | 0 | Yes |
| 17p indolent | ||||||
| 26 | 12.0 | 47.0 | 95.4 | 0.6 | 61 | No |
| 28 | 28.0 | 81.0 | 89.9 | 13.2 | 55 | No |
| 102b | 8.0 | 15.0 | 94.0 | 6.3 | 74 | No |
| 103 | 11.0 | 0.0 | 93.0 | 6.4 | 55 | Yes |
| 107 | 14.0 | 90.0 | 94.7 | 2.2 | 30 | No |
| 108 | 86.5 | 0.0 | 89.0 | 4.2 | 25 | No |
| 110 | 8.0 | 62.0 | 90.9 | 11.7 | 24 | No |
| 111 | 29.0 | 0.0 | 92.0 | 0.7 | 24 | No |
| 112 | 14.0 | 15/38 | 97.6 | 4.3 | 27 | No |
| 19 | 61.0 | 2.0 | 99.6 | 51.5 | 39 | No |
| Subgroup/patient no. . | 17p del (% positive cells) . | 13q del (% positive cells) . | IGHV % homology . | ZAP-70+ cells, % . | TTT, mos . | Therapy . |
|---|---|---|---|---|---|---|
| 17p aggressive | ||||||
| 16 | 84.0 | 52.0 | 99.3 | 50.2 | 0 | Yes |
| 17 | 86.0 | 49.5 | 99.6 | 76.8 | 0 | Yes |
| 100 | 7.5 | 59.0 | 88.4 | 3.8 | 24 | Yes |
| 20 | 96.0 | 0.0 | 99.6 | 36.4 | 0 | Yes |
| 21 | 76.0 | 70.0 | 99.3 | 36.5 | 0 | Yes |
| 22 | 93.0 | 94.5 | 99.6 | 84.8 | 0 | Yes |
| 23 | 61.0 | 15.0 | 99.3 | 42.6 | 0.5 | Yes |
| 24 | 69.5 | 70.0 | 99.6 | 53.7 | 6 | Yes |
| 114 | 9.0 | 40.0 | 90.6 | 6.0 | 0 | Yes |
| 17p indolent | ||||||
| 26 | 12.0 | 47.0 | 95.4 | 0.6 | 61 | No |
| 28 | 28.0 | 81.0 | 89.9 | 13.2 | 55 | No |
| 102b | 8.0 | 15.0 | 94.0 | 6.3 | 74 | No |
| 103 | 11.0 | 0.0 | 93.0 | 6.4 | 55 | Yes |
| 107 | 14.0 | 90.0 | 94.7 | 2.2 | 30 | No |
| 108 | 86.5 | 0.0 | 89.0 | 4.2 | 25 | No |
| 110 | 8.0 | 62.0 | 90.9 | 11.7 | 24 | No |
| 111 | 29.0 | 0.0 | 92.0 | 0.7 | 24 | No |
| 112 | 14.0 | 15/38 | 97.6 | 4.3 | 27 | No |
| 19 | 61.0 | 2.0 | 99.6 | 51.5 | 39 | No |
TTT indicates time to treatment; and ZAP-70, ζ-associated protein 70.