Significantly up-regulated pathways
| Rank . | Pathway name . | No. of genes . | Gamma P value . |
|---|---|---|---|
| 1 | Cytokine-cytokine receptor interaction | 17 | .001 |
| 2 | Cell adhesion molecules (CAMs) | 8 | .001 |
| 3 | Epithelial cell signaling in Helicobacter pylori infection | 9 | .001 |
| 4 | Leukocyte transendothelial migration | 5 | .001 |
| 5 | Apoptosis | 12 | .001 |
| 6 | Toll-like receptor signaling pathway | 10 | .001 |
| 7 | Small cell lung cancer | 10 | .001 |
| 8 | B-cell receptor signaling pathway | 8 | .001 |
| 9 | MAPK signaling pathway | 16 | .001 |
| 10 | T-cell receptor signaling pathway | 9 | .001 |
| 11 | ErbB signaling pathway | 8 | .001 |
| 12 | Natural killer cell–mediated cytotoxicity | 9 | .002 |
| 13 | Jak-STAT signaling pathway | 9 | .003 |
| 14 | Adipocytokine signaling pathway | 6 | .006 |
| 15 | Complement and coagulation cascades | 6 | .008 |
| 16 | Chronic myeloid leukemia | 6 | .01 |
| 17 | TGF-beta signaling pathway | 6 | .01 |
| 18 | Pancreatic cancer | 5 | .039 |
| 19 | Antigen processing and presentation | 5 | .047 |
| Rank . | Pathway name . | No. of genes . | Gamma P value . |
|---|---|---|---|
| 1 | Cytokine-cytokine receptor interaction | 17 | .001 |
| 2 | Cell adhesion molecules (CAMs) | 8 | .001 |
| 3 | Epithelial cell signaling in Helicobacter pylori infection | 9 | .001 |
| 4 | Leukocyte transendothelial migration | 5 | .001 |
| 5 | Apoptosis | 12 | .001 |
| 6 | Toll-like receptor signaling pathway | 10 | .001 |
| 7 | Small cell lung cancer | 10 | .001 |
| 8 | B-cell receptor signaling pathway | 8 | .001 |
| 9 | MAPK signaling pathway | 16 | .001 |
| 10 | T-cell receptor signaling pathway | 9 | .001 |
| 11 | ErbB signaling pathway | 8 | .001 |
| 12 | Natural killer cell–mediated cytotoxicity | 9 | .002 |
| 13 | Jak-STAT signaling pathway | 9 | .003 |
| 14 | Adipocytokine signaling pathway | 6 | .006 |
| 15 | Complement and coagulation cascades | 6 | .008 |
| 16 | Chronic myeloid leukemia | 6 | .01 |
| 17 | TGF-beta signaling pathway | 6 | .01 |
| 18 | Pancreatic cancer | 5 | .039 |
| 19 | Antigen processing and presentation | 5 | .047 |
Selection of pathways was based upon number of genes more than 5 and significance (gamma P < .05). Pathway rankings are based on significance.