Presenting clinical and laboratory findings in 241 FLT3-ITD–mutated AML patients
| Characteristic . | No. . |
|---|---|
| Sex (male/female) | 100/141 (41/59) |
| Type of AML, no. (%) | |
| De novo | 224 (92.9) |
| s-AML | 11 (4.6) |
| t-AML | 6 (2.5) |
| Median age, y (range) | 47.0 (18-60) |
| Median WBC count, ×109/L (range) | 44.4 (0.2-372) |
| Missing | 8 |
| Median platelet count, ×109/L | 61.0 (8-688) |
| Missing | 8 |
| Median hemoglobin level, g/L (range) | 89 (31-146) |
| Missing | 8 |
| Median BM blasts, % (range) | 85.0 (0-100) |
| Missing | 20 |
| Median PB blasts, % (range) | 64.0 (0-100) |
| Missing | 16 |
| Median LDH, U/L (range) | 584.0 (122-4610) |
| Missing | 16 |
| Karyotype, no. (%) | |
| Normal | 208 (86.3) |
| Abnormal | 28 (11.6) |
| Missing | 5 (2.1) |
| Cytogenetic risk group, no. (%) | |
| Favorable risk | 2 (0.8) |
| Intermediate I (normal karyotype) | 208 (86.3) |
| Intermediate II (other karyotypes) | 18 (7.5) |
| High risk | 8 (3.3) |
| Characteristic . | No. . |
|---|---|
| Sex (male/female) | 100/141 (41/59) |
| Type of AML, no. (%) | |
| De novo | 224 (92.9) |
| s-AML | 11 (4.6) |
| t-AML | 6 (2.5) |
| Median age, y (range) | 47.0 (18-60) |
| Median WBC count, ×109/L (range) | 44.4 (0.2-372) |
| Missing | 8 |
| Median platelet count, ×109/L | 61.0 (8-688) |
| Missing | 8 |
| Median hemoglobin level, g/L (range) | 89 (31-146) |
| Missing | 8 |
| Median BM blasts, % (range) | 85.0 (0-100) |
| Missing | 20 |
| Median PB blasts, % (range) | 64.0 (0-100) |
| Missing | 16 |
| Median LDH, U/L (range) | 584.0 (122-4610) |
| Missing | 16 |
| Karyotype, no. (%) | |
| Normal | 208 (86.3) |
| Abnormal | 28 (11.6) |
| Missing | 5 (2.1) |
| Cytogenetic risk group, no. (%) | |
| Favorable risk | 2 (0.8) |
| Intermediate I (normal karyotype) | 208 (86.3) |
| Intermediate II (other karyotypes) | 18 (7.5) |
| High risk | 8 (3.3) |
AML indicates acute myeloid leukemia; s-AML, AML after a preceding myelodysplastic syndrome; t-AML, AML after chemotherapy and/or radiation therapy; WBC, white blood cell; BM, bone marrow; PB, peripheral blood; and LDH, lactate dehydrogenase.