Bone marrow findings
Patient no. . | Age at biopsy . | Bone marrow cellularity, % . | M:E ratio . | Granulocytic series . | Erythroid series . | Megakaryocytes . | Eosinophils . | Monocytic precursors . | Other . |
---|---|---|---|---|---|---|---|---|---|
ADA1 | 21 y | 20 | 2:1 | Mild left shift | Megaloblastic | Hypolobated | Mild increase | Mild increase | NA |
ADA5 | 8 y | 30 | 1:1 | Normal | Normal | Small, hypolobulated | Left-shifted | Normal | NA |
ADA6 | 6 y | 30-40 | 1:1 | Left shift | Megaloblastic | Normal | Increased, left-shifted | Mild increase | NA |
ADA10 | 16 mo | 60 | 1:1 | Left shift, megaloblastic, rare pseudo-Pelger-Hüet cells | Normal | Monolobated, micromegakaryocytes | Left-shifted | Normal | Paratrabecular fibrosis, increased hematogones |
ADA14 | 2.5 y | 50 | 2-1:1 | Mild left shift | Megaloblastic | Few hypolobated | Normal | Mild increase | Increased hematogones |
ADA16 | 2 y | NA | NA | Mild left shift | Megaloblastic, rare nuclear budding | Hypolobated, monolobated | Left-shifted | Mild increase | NA |
Patient no. . | Age at biopsy . | Bone marrow cellularity, % . | M:E ratio . | Granulocytic series . | Erythroid series . | Megakaryocytes . | Eosinophils . | Monocytic precursors . | Other . |
---|---|---|---|---|---|---|---|---|---|
ADA1 | 21 y | 20 | 2:1 | Mild left shift | Megaloblastic | Hypolobated | Mild increase | Mild increase | NA |
ADA5 | 8 y | 30 | 1:1 | Normal | Normal | Small, hypolobulated | Left-shifted | Normal | NA |
ADA6 | 6 y | 30-40 | 1:1 | Left shift | Megaloblastic | Normal | Increased, left-shifted | Mild increase | NA |
ADA10 | 16 mo | 60 | 1:1 | Left shift, megaloblastic, rare pseudo-Pelger-Hüet cells | Normal | Monolobated, micromegakaryocytes | Left-shifted | Normal | Paratrabecular fibrosis, increased hematogones |
ADA14 | 2.5 y | 50 | 2-1:1 | Mild left shift | Megaloblastic | Few hypolobated | Normal | Mild increase | Increased hematogones |
ADA16 | 2 y | NA | NA | Mild left shift | Megaloblastic, rare nuclear budding | Hypolobated, monolobated | Left-shifted | Mild increase | NA |
NA indicates not applicable; and M:E, myeloid:erythroid.