Differentiation pattern of hESC-derived cells
Cell type . | % of total cells . | ||
---|---|---|---|
Day 7 . | Day 10 . | Day 13 . | |
Myeloblasts | 61.0 ± 9.1 | 2.3 ± 1.2 | ND |
Promyelocytes | 16.8 ± 6.3 | 8.5 ± 0.9 | 0.7 ± 0.8 |
Myelocytes | 12.3 ± 4.8 | 34.0 ± 6.8 | 6.4 ± 3.4 |
Metamyelocytes | 3.0 ± 1.0 | 19.0 ± 1.3 | 10.2 ± 4.3 |
Stab neutrophils | 0.8 ± 0.3 | 16.2 ± 3.0 | 18.3 ± 2.6 |
Segmented neutrophils | 0.3 ± 0.6 | 14.7 ± 6.0 | 53.1 ± 9.6 |
Macrophage/monocytes | 5.7 ± 0.6 | 5.3 ± 1.3 | 11.2 ± 1.4 |
Mature neutrophils | 1.2 ± 0.8 | 30.8 ± 4.6 | 71.4 ± 7.4 |
Cell type . | % of total cells . | ||
---|---|---|---|
Day 7 . | Day 10 . | Day 13 . | |
Myeloblasts | 61.0 ± 9.1 | 2.3 ± 1.2 | ND |
Promyelocytes | 16.8 ± 6.3 | 8.5 ± 0.9 | 0.7 ± 0.8 |
Myelocytes | 12.3 ± 4.8 | 34.0 ± 6.8 | 6.4 ± 3.4 |
Metamyelocytes | 3.0 ± 1.0 | 19.0 ± 1.3 | 10.2 ± 4.3 |
Stab neutrophils | 0.8 ± 0.3 | 16.2 ± 3.0 | 18.3 ± 2.6 |
Segmented neutrophils | 0.3 ± 0.6 | 14.7 ± 6.0 | 53.1 ± 9.6 |
Macrophage/monocytes | 5.7 ± 0.6 | 5.3 ± 1.3 | 11.2 ± 1.4 |
Mature neutrophils | 1.2 ± 0.8 | 30.8 ± 4.6 | 71.4 ± 7.4 |
The sum of the stab and segmented neutrophils indicates the total mature neutrophils. Data are shown as mean plus or minus SD (n = 3 independent experiments).
ND indicates not detectable.