Probability of achieving an MMR and the risk of developing an event according to the reduction of BCR-ABL1 transcripts at fixed time points
| BCR-ABL1/ABL1 transcript ratio . | Percentage probability of outcome according to transcript ratio at specified time points (median months to outcome) . | |||||
|---|---|---|---|---|---|---|
| MMR (BCR-ABL1/ABL1< 0.05%) . | Event . | |||||
| 3 mo . | 6 mo . | 12 mo . | 3 mo . | 6 mo . | 12 mo . | |
| ≤ 0.1% | 100 (3) | 96 (6) | 97 (12) | 4 (13) | 1 (38) | 3 (40) |
| > 0.1% to 1% | 84 (6) | 69 (12) | 61 (18) | 3 (46) | 7 (30) | 2 (48) |
| > 1% to 10% | 53 (17) | 44 (18) | 20 (33) | 11 (21) | 9 (34) | 8 (47) |
| > 10% | 33 (15) | 15 (18) | 7 (46) | 13 (47) | 23 (14) | 50 (19) |
| BCR-ABL1/ABL1 transcript ratio . | Percentage probability of outcome according to transcript ratio at specified time points (median months to outcome) . | |||||
|---|---|---|---|---|---|---|
| MMR (BCR-ABL1/ABL1< 0.05%) . | Event . | |||||
| 3 mo . | 6 mo . | 12 mo . | 3 mo . | 6 mo . | 12 mo . | |
| ≤ 0.1% | 100 (3) | 96 (6) | 97 (12) | 4 (13) | 1 (38) | 3 (40) |
| > 0.1% to 1% | 84 (6) | 69 (12) | 61 (18) | 3 (46) | 7 (30) | 2 (48) |
| > 1% to 10% | 53 (17) | 44 (18) | 20 (33) | 11 (21) | 9 (34) | 8 (47) |
| > 10% | 33 (15) | 15 (18) | 7 (46) | 13 (47) | 23 (14) | 50 (19) |