Nonhematologic toxicities (grades 3 and 4) of S-HAM compared with double induction in the AML-CG 99 trial (de novo AML, age <60 years, HAM-HAM double induction)
| Toxicity . | S-HAM AML-CG 2004, % . | HAM-HAM AML-CG 1999, % . |
|---|---|---|
| Nausea | 9 | 16 |
| Stomatitis | 3 | 9 |
| Diarrhea | 14 | 14 |
| Hemorrhage | 8 | 8 |
| Infection | 40 | 56 |
| Cardiac event | 6 | 5 |
| Central nervous system toxicity | 5 | 5 |
| Toxicity . | S-HAM AML-CG 2004, % . | HAM-HAM AML-CG 1999, % . |
|---|---|---|
| Nausea | 9 | 16 |
| Stomatitis | 3 | 9 |
| Diarrhea | 14 | 14 |
| Hemorrhage | 8 | 8 |
| Infection | 40 | 56 |
| Cardiac event | 6 | 5 |
| Central nervous system toxicity | 5 | 5 |