Production of PGE2 by MSCs cultured alone or cocultured with NK cells (in the presence or in the absence of the PGE2 inhibitor NS-398)
Experiment no. . | MSC . | NK plus MSC . | NK plus MSC plus NS-398 . |
---|---|---|---|
1 | 11250 | 36000 | 1000 |
2 | 11250 | 37500 | 1500 |
3 | 3600 | 23000 | 45 |
4 | 3600 | 20000 | 40 |
5 | 1000 | 16500 | 2500 |
6 | 1000 | 120000 | 2700 |
Mean | 4090 | 42167 | 1298 |
SD | 4208 | 39078 | 1157 |
Experiment no. . | MSC . | NK plus MSC . | NK plus MSC plus NS-398 . |
---|---|---|---|
1 | 11250 | 36000 | 1000 |
2 | 11250 | 37500 | 1500 |
3 | 3600 | 23000 | 45 |
4 | 3600 | 20000 | 40 |
5 | 1000 | 16500 | 2500 |
6 | 1000 | 120000 | 2700 |
Mean | 4090 | 42167 | 1298 |
SD | 4208 | 39078 | 1157 |
Data refer to the levels of PGE2 expressed as pg/mL. The levels of PGE2 were evaluated in supernatants after 72 hours of culture.