Time series overlapping spectratype analysis of T-cell repertoires of the MLC and the posttransplantation patient samples
| Vβ . | Patient no. . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 . | 3 . | 4 . | 5 . | 7 . | 8 . | 9 . | 10 . | 11 . | 12 . | 13 . | 14 . | 17 . | |
| 1 | −/−/−* | −/− | −/N/−/−* | +/+/N/− | +/+/+/− | −/− | +/+/+ | −/N | +/+/+ | N | −/−/−/N/−* | +/+/+/N | −/−/−/−* |
| 2 | N | +/+ | +/−/−/+ | +/+/N/− | +/+/−/+ | −/−* | +/+/+ | −/N | −/N/− | +/+ | +/N/N/−/+ | −/−/−/− | +/−/+/+ |
| 3 | N | N/+ | N | N/+/−/N | −/−/−/−* | −/−* | +/+/− | +/+ | +/−/+ | +/+ | −/−/−/−/+* | −/+/+/+ | +/−/+/+ |
| 4 | +/+/+ | −/+ | +/+/+/+ | −/+/−/N | N | N/+ | +/+/N | +/+ | −/N/− | −/N | +/N/+/N/N | −/−/−/N | −/N/−/N |
| 5 | −/−/+ | N/− | +/−/+/+ | +/−/N/N | −/−/−/−* | +/+ | −/+/+ | N* | +/+/+ | +/+ | +/−/+/+/+ | −/−/−/− | −/−/−/−* |
| 6 | +/+/+ | N/− | +/+/+/− | +/+/+/+ | −/−/−/+ | −/−* | −/N/N | +/N | +/+/N | −/−* | +/N+/− | −/+/+/+ | −/−/+/−* |
| 7 | N | −/−* | N/−/−/−* | N/N/+/+ | +/+/+/− | N | −/−/−* | N | +/N/+ | −/N | +/+/+/ND/− | +/+/+/N | −/−/N/−* |
| 8 | −/−/−/* | +/+ | +/+/+/+ | N/−/+/N | N | +/− | +/+/+ | N | −/+/+ | +/+ | +/−/−/−/−* | N | +/+/+/+ |
| 9 | +/+/+ | +/+ | +/+/+/+ | N/N/−/+ | +/+/+/+ | −/− | +/+/+ | +/N | +/+/+ | +/+ | −/−/−/−/−* | +/+/+/+ | −/−/−/−* |
| 11 | N | N/− | N/+/+/+ | N/−/−/−* | +/+/+/+ | N | −/−/−* | −/+ | −/+/N | +/+ | N/N/+/N/+ | +/−/+/−* | +/+/N/− |
| 12 | N/+/N | N/+ | N | +/+/+/N | N | −/− | N | +/+ | N | N/− | +/N/+/N/+ | N/N/+/N | ND |
| 13 | +/+/+ | +/− | +/+/−/+ | +/+/+/N | −/+/+/N | +/+ | −/+/+ | N/+ | N/+/+ | +/+ | −/N/−/N/N* | N/+/+/+ | ND |
| 14 | +/+/+ | N | N | N/+/N/+ | +/−/−/+ | N/+ | +/+/+ | N | N | N | +/N/+/+/N | +/+/+/+ | N/+/+/+ |
| 15 | −/−/− | N/+ | +/+/+/+ | N/+/+/+ | +/+/+/+ | −/− | +/+/+ | N/+ | +/−/−* | +/+ | +/N/+/N/N | −/N/+/+ | +/+/+/+ |
| 16 | −/+/− | −/− | +/−/+/− | +/+/+/+ | −/−/−/−/* | N | +/+/N | +/+ | N | +/+ | −/−/−/−/−* | −/−/−/−* | +/+/+/− |
| 17 | −/+/+ | −/+ | N/−/−/− | N/+/−/+ | −/−/−/− | −/+ | +/−/−* | N | +/+/N | +/+ | +/−/+/−/+* | +/+/+/− | −/+/+/+ |
| 18 | N/N/+ | N | N/N/−/N | N/+/N/+ | N | N | +/+/− | N | −/N/− | N | N | +/−/−/N | −/−/−/−* |
| 19 | +/+/−* | −/+ | N | −/+/N/+ | +/N/+/+ | +/− | +/+/+ | N | +/+/+ | +/+ | −/N/+/+/N | −/+/−/+ | −/+/+/+ |
| 21 | +/+/N | N | N/+/+/+ | N/N/+/N | N | N | +/+/+ | N | N/N/+ | N | N | N− | N/N/+/N |
| 22 | N | N | N | N/+/N/N | N/N/−/N | N | +/+/− | N | N | N | N | +/N−+/+ | +/+/+/− |
| 23 | +/+/+ | +/+ | +/+/+/+ | N/N/−/N | +/−/−/+ | +/+ | +/−/− | −/N | N/−/− | +/+ | −/N/+/+/+ | −/+/−/− | +/+/−/+ |
| % | 89 | 57 | 91 | 67 | 80 | 75 | 100 | 80 | 80 | 100 | 63 | 83 | 100 |
| Vβ . | Patient no. . | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 . | 3 . | 4 . | 5 . | 7 . | 8 . | 9 . | 10 . | 11 . | 12 . | 13 . | 14 . | 17 . | |
| 1 | −/−/−* | −/− | −/N/−/−* | +/+/N/− | +/+/+/− | −/− | +/+/+ | −/N | +/+/+ | N | −/−/−/N/−* | +/+/+/N | −/−/−/−* |
| 2 | N | +/+ | +/−/−/+ | +/+/N/− | +/+/−/+ | −/−* | +/+/+ | −/N | −/N/− | +/+ | +/N/N/−/+ | −/−/−/− | +/−/+/+ |
| 3 | N | N/+ | N | N/+/−/N | −/−/−/−* | −/−* | +/+/− | +/+ | +/−/+ | +/+ | −/−/−/−/+* | −/+/+/+ | +/−/+/+ |
| 4 | +/+/+ | −/+ | +/+/+/+ | −/+/−/N | N | N/+ | +/+/N | +/+ | −/N/− | −/N | +/N/+/N/N | −/−/−/N | −/N/−/N |
| 5 | −/−/+ | N/− | +/−/+/+ | +/−/N/N | −/−/−/−* | +/+ | −/+/+ | N* | +/+/+ | +/+ | +/−/+/+/+ | −/−/−/− | −/−/−/−* |
| 6 | +/+/+ | N/− | +/+/+/− | +/+/+/+ | −/−/−/+ | −/−* | −/N/N | +/N | +/+/N | −/−* | +/N+/− | −/+/+/+ | −/−/+/−* |
| 7 | N | −/−* | N/−/−/−* | N/N/+/+ | +/+/+/− | N | −/−/−* | N | +/N/+ | −/N | +/+/+/ND/− | +/+/+/N | −/−/N/−* |
| 8 | −/−/−/* | +/+ | +/+/+/+ | N/−/+/N | N | +/− | +/+/+ | N | −/+/+ | +/+ | +/−/−/−/−* | N | +/+/+/+ |
| 9 | +/+/+ | +/+ | +/+/+/+ | N/N/−/+ | +/+/+/+ | −/− | +/+/+ | +/N | +/+/+ | +/+ | −/−/−/−/−* | +/+/+/+ | −/−/−/−* |
| 11 | N | N/− | N/+/+/+ | N/−/−/−* | +/+/+/+ | N | −/−/−* | −/+ | −/+/N | +/+ | N/N/+/N/+ | +/−/+/−* | +/+/N/− |
| 12 | N/+/N | N/+ | N | +/+/+/N | N | −/− | N | +/+ | N | N/− | +/N/+/N/+ | N/N/+/N | ND |
| 13 | +/+/+ | +/− | +/+/−/+ | +/+/+/N | −/+/+/N | +/+ | −/+/+ | N/+ | N/+/+ | +/+ | −/N/−/N/N* | N/+/+/+ | ND |
| 14 | +/+/+ | N | N | N/+/N/+ | +/−/−/+ | N/+ | +/+/+ | N | N | N | +/N/+/+/N | +/+/+/+ | N/+/+/+ |
| 15 | −/−/− | N/+ | +/+/+/+ | N/+/+/+ | +/+/+/+ | −/− | +/+/+ | N/+ | +/−/−* | +/+ | +/N/+/N/N | −/N/+/+ | +/+/+/+ |
| 16 | −/+/− | −/− | +/−/+/− | +/+/+/+ | −/−/−/−/* | N | +/+/N | +/+ | N | +/+ | −/−/−/−/−* | −/−/−/−* | +/+/+/− |
| 17 | −/+/+ | −/+ | N/−/−/− | N/+/−/+ | −/−/−/− | −/+ | +/−/−* | N | +/+/N | +/+ | +/−/+/−/+* | +/+/+/− | −/+/+/+ |
| 18 | N/N/+ | N | N/N/−/N | N/+/N/+ | N | N | +/+/− | N | −/N/− | N | N | +/−/−/N | −/−/−/−* |
| 19 | +/+/−* | −/+ | N | −/+/N/+ | +/N/+/+ | +/− | +/+/+ | N | +/+/+ | +/+ | −/N/+/+/N | −/+/−/+ | −/+/+/+ |
| 21 | +/+/N | N | N/+/+/+ | N/N/+/N | N | N | +/+/+ | N | N/N/+ | N | N | N− | N/N/+/N |
| 22 | N | N | N | N/+/N/N | N/N/−/N | N | +/+/− | N | N | N | N | +/N−+/+ | +/+/+/− |
| 23 | +/+/+ | +/+ | +/+/+/+ | N/N/−/N | +/−/−/+ | +/+ | +/−/− | −/N | N/−/− | +/+ | −/N/+/+/+ | −/+/−/− | +/+/−/+ |
| % | 89 | 57 | 91 | 67 | 80 | 75 | 100 | 80 | 80 | 100 | 63 | 83 | 100 |
Posttransplantation time points are separated by a shill (/).
% indicates the overall percentage of time series overlapping Vβ family spectratypes between the MLC and patient posttransplantation sample; +, overlapping spectratype between the MLC and the posttransplantation sample; −, no overlap; and N, not determined
Multiple posttransplantation samples with overlapping skewing, not overlapping with the MLC.