Table 4

Comparison of addiction and substance abuse in adults with sickle cell disease and those in the community at-large

Population/locationYearAge, yAddiction or substance abuse, no./no. (%)
Adult SCD patients    
    Cincinnati44  1989 Not stated 14/160 (9) 
    Philadelphia45  1992 Not stated 0/50 (0) 
    London46  2002 Not stated 4/800 (0.5) 
    New Haven* 2007 All 8/96 (8.3) 
  18-25 2/31 (6.5) 
Community at-large    
    St Louis47  1981-82 Lifelong 6.4 ± 1.0% 
    Baltimore47  1981-82 Lifelong 7.3 ± 0.9% 
    New Haven47  1980-81 Lifelong 6.4 ± 1.3% 
    Connecticut48  2004-05 18-25 8.83% (6.90-11.23)§ 
Population/locationYearAge, yAddiction or substance abuse, no./no. (%)
Adult SCD patients    
    Cincinnati44  1989 Not stated 14/160 (9) 
    Philadelphia45  1992 Not stated 0/50 (0) 
    London46  2002 Not stated 4/800 (0.5) 
    New Haven* 2007 All 8/96 (8.3) 
  18-25 2/31 (6.5) 
Community at-large    
    St Louis47  1981-82 Lifelong 6.4 ± 1.0% 
    Baltimore47  1981-82 Lifelong 7.3 ± 0.9% 
    New Haven47  1980-81 Lifelong 6.4 ± 1.3% 
    Connecticut48  2004-05 18-25 8.83% (6.90-11.23)§ 

SCD indicates sickle cell disease.

*

Solomon, unpublished observations, June 2007, based on criteria of Savage.49 

All patients were on long-acting opioids for 2 years.

Values are means ± SEM for African-Americans as %.

§

Numbers in parentheses are 95% prediction interval as %.

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