Comparison of actual opioid use in adults in different acute pain settings
| Clinical setting . | Reference . | N . | Opioid use in first 24 hours . |
|---|---|---|---|
| VOC in SCD | Solomon* | 24 | 64.7 ± 41.0 (16-157) |
| Postoperative | |||
| Liver resection | Roy et al32 | 10 | 87 ± 34 |
| Spinal surgery | Jarvey et al33 | 20 | 51.1 ± 20.8 |
| Total abdominal hysterectomy | Gan et al34 | 20 | 59.1 ± 27.4† |
| C-section | Bell et al35 | 28 | 67 ± 28 |
| Knee surgery | Loper and Ready36 | 17 | 64 ± 24 (32-101) |
| Clinical setting . | Reference . | N . | Opioid use in first 24 hours . |
|---|---|---|---|
| VOC in SCD | Solomon* | 24 | 64.7 ± 41.0 (16-157) |
| Postoperative | |||
| Liver resection | Roy et al32 | 10 | 87 ± 34 |
| Spinal surgery | Jarvey et al33 | 20 | 51.1 ± 20.8 |
| Total abdominal hysterectomy | Gan et al34 | 20 | 59.1 ± 27.4† |
| C-section | Bell et al35 | 28 | 67 ± 28 |
| Knee surgery | Loper and Ready36 | 17 | 64 ± 24 (32-101) |
Opioid use values are given as means plus or minus 1 standard deviation for intravenous morphine equivalents except where noted, and numbers in parentheses are ranges of doses administered.
VOC indicates vaso-occlusive crisis; SCD, sickle cell disease; and C-section, caesarian section.
Unpublished observations for 24 consecutive in-patient hospital admissions in 21 adult SCD patients from March 1, 2006, through February 28, 2007, who were not on chronic long-acting opioids.
Value is mean plus or minus 1 SEM.