Spectral karyotyping of thymic lymphomas
| Tumor . | Genotype . | Translocations . | Frequency . | Flow cytometry . |
|---|---|---|---|---|
| 83 | RAG1S723C/S723Cp53−/− | t(8;17) | 20/20 | CD4+CD8+TCRβ− |
| [2 translocated chromosomes per metaphase] | CD8SP | |||
| 135 | RAG1S723C/S723Cp53−/− | t(15;12) | 2/18 | CD4+CD8+TCRβ− |
| t(10;5) | 1/18 | |||
| S542 | RAG1S723C/S723Cp53−/− | Chr 15;15 SAFs | 16/18 | CD4+CD8+TCRβ− |
| Chr 12;12 SAFs | 5/18 | |||
| t(5;19) | 1/18 | |||
| S642 | RAG1S723C/S723Cp53−/− | Chr 3;6 SAFs | 5/24 | CD4−CD8− |
| t(14;1) | 2/24 | |||
| S779 | RAG1S723C/S723Cp53−/− | t(15;12) | 1/18 | CD4+CD8+TCRβ− |
| S878 | RAG1S723C/S723Cp53−/− | t(15;9) | 17/18 | CD4−CD8+TCRβ− |
| S922 | RAG1S723C/S723Cp53−/− | t(14;8) | 11/22 | CD4+CD8+TCRβ− |
| S786 | RAG1+/S723Cp53−/− | t(9;11) | 2/9 | CD4+CD8+TCRβ+ |
| S801 | RAG1+/S723Cp53−/− | Chr 15;15 SAFs | 28/33 | CD4+CD8+TCRβ− |
| Chr 11;11 SAFs | 22/33 | |||
| Chr X;X SAFs | 5/33 | |||
| Chr 16;16 SAFs | 4/33 | |||
| Chr 6;6 SAFs | 4/33 | |||
| Chr 3;3 SAFs | 2/33 | |||
| t(16;12) | 1/33 | |||
| S900 | RAG1+/S723Cp53−/− | Chr 5;5 SAFs | 15/24 | CD4+CD8+TCRβ+ |
| t(11;16) | 13/24 | |||
| S771 | RAG1+/+p53−/− | None | 0/19 | CD4−CD8+TCRβ+ |
| S839 | RAG1+/+p53−/− | None | 0/20 | CD4−CD8+TCRβ+ |
| S908 | RAG1+/+p53−/− | None | 0/27 | CD4+CD8+TCRβ+ |
| S919 | RAG1+/+p53−/− | None | 0/12 | CD4−CD8+TCRβ+ |
| S926 | RAG1+/+p53−/− | None | 0/20 | CD4−CD8+TCRβ+ |
| S1324 | RAG1+/+p53−/− | t(15;14) | 22/25 | CD4+CD8+TCRβ− |
| Tumor . | Genotype . | Translocations . | Frequency . | Flow cytometry . |
|---|---|---|---|---|
| 83 | RAG1S723C/S723Cp53−/− | t(8;17) | 20/20 | CD4+CD8+TCRβ− |
| [2 translocated chromosomes per metaphase] | CD8SP | |||
| 135 | RAG1S723C/S723Cp53−/− | t(15;12) | 2/18 | CD4+CD8+TCRβ− |
| t(10;5) | 1/18 | |||
| S542 | RAG1S723C/S723Cp53−/− | Chr 15;15 SAFs | 16/18 | CD4+CD8+TCRβ− |
| Chr 12;12 SAFs | 5/18 | |||
| t(5;19) | 1/18 | |||
| S642 | RAG1S723C/S723Cp53−/− | Chr 3;6 SAFs | 5/24 | CD4−CD8− |
| t(14;1) | 2/24 | |||
| S779 | RAG1S723C/S723Cp53−/− | t(15;12) | 1/18 | CD4+CD8+TCRβ− |
| S878 | RAG1S723C/S723Cp53−/− | t(15;9) | 17/18 | CD4−CD8+TCRβ− |
| S922 | RAG1S723C/S723Cp53−/− | t(14;8) | 11/22 | CD4+CD8+TCRβ− |
| S786 | RAG1+/S723Cp53−/− | t(9;11) | 2/9 | CD4+CD8+TCRβ+ |
| S801 | RAG1+/S723Cp53−/− | Chr 15;15 SAFs | 28/33 | CD4+CD8+TCRβ− |
| Chr 11;11 SAFs | 22/33 | |||
| Chr X;X SAFs | 5/33 | |||
| Chr 16;16 SAFs | 4/33 | |||
| Chr 6;6 SAFs | 4/33 | |||
| Chr 3;3 SAFs | 2/33 | |||
| t(16;12) | 1/33 | |||
| S900 | RAG1+/S723Cp53−/− | Chr 5;5 SAFs | 15/24 | CD4+CD8+TCRβ+ |
| t(11;16) | 13/24 | |||
| S771 | RAG1+/+p53−/− | None | 0/19 | CD4−CD8+TCRβ+ |
| S839 | RAG1+/+p53−/− | None | 0/20 | CD4−CD8+TCRβ+ |
| S908 | RAG1+/+p53−/− | None | 0/27 | CD4+CD8+TCRβ+ |
| S919 | RAG1+/+p53−/− | None | 0/12 | CD4−CD8+TCRβ+ |
| S926 | RAG1+/+p53−/− | None | 0/20 | CD4−CD8+TCRβ+ |
| S1324 | RAG1+/+p53−/− | t(15;14) | 22/25 | CD4+CD8+TCRβ− |
SAFs indicates short-arm fusions.