List of differentially expressed genes in leukemic LGLs compared with activated enriched CD8+ cells that belong to GO category apoptosis (GO:0006915)
| Gene symbol . | Fold change in leukemic LGLs compared with activated enriched CD8+ cells . | Gene description . |
|---|---|---|
| TNFAIP3 | 6.73 | TNF-alpha–induced protein 3 |
| GZMH | 6.50 | Granzyme H |
| BCL2A1 | 4.47 | BCL2-related protein A1 |
| LITAF | 3.78 | Lipopolysaccharide-induced TNF factor |
| TNFSF13 | 3.73 | TNF superfamily, member 13 |
| CTSB | 3.46 | Cathepsin B |
| FAIM3 | 3.43 | Fas apoptotic inhibitory molecule 3 |
| CASP8 | 3.41 | Caspase-8 |
| SERPINB9 | 3.36 | Serpin peptidase inhibitor, clade B |
| GADD45B | 3.36 | Growth arrest and DNA-damage inducible, beta |
| RHOT2 | 2.71 | Ras homolog gene family, member T2 |
| RAF1 | 2.28 | v-raf-1 leukemia viral oncogene homolog 1 |
| NFKBIA | 2.27 | Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
| MCL1 | 2.25 | Myeloid cell leukemia sequence 1 (BCL2 related) |
| PDCD4 | 2.19 | Programmed cell death 4 |
| TP53BP2 | 2.19 | Tumor protein p53 binding protein, 2 |
| PRF1 | 2.16 | Perforin 1 |
| RELA | 2.13 | v-rel,p65 |
| TP53 | 0.50 | Tumor protein p53 |
| TNFAIP8 | 0.47 | TNF alpha-induced protein 8 |
| CASP3 | 0.46 | Caspase-3 |
| STAT1 | 0.45 | Signal transducer and activator of transcription 1 |
| IL2RB | 0.44 | Interleukin 2 receptor, beta |
| LCK | 0.41 | Lymphocyte-specific protein tyrosine kinase |
| FAS | 0.37 | Fas (TNFSF6) |
| SIVA | 0.33 | CD27-binding (Siva) protein |
| BAG2 | 0.23 | BCL2-associated athanogene 2 |
| BAX | 0.22 | BCL2-associated X protein |
| BCL2 | 0.21 | B-cell CLL |
| GZMA | 0.17 | Granzyme A |
| PRDX2 | 0.16 | Peroxiredoxin 2 |
| CASP6 | 0.15 | Caspase-6 |
| TNFSF10 | 0.15 | TNF superfamily, member 10 |
| TUBB | 0.10 | Tubulin, beta |
| Gene symbol . | Fold change in leukemic LGLs compared with activated enriched CD8+ cells . | Gene description . |
|---|---|---|
| TNFAIP3 | 6.73 | TNF-alpha–induced protein 3 |
| GZMH | 6.50 | Granzyme H |
| BCL2A1 | 4.47 | BCL2-related protein A1 |
| LITAF | 3.78 | Lipopolysaccharide-induced TNF factor |
| TNFSF13 | 3.73 | TNF superfamily, member 13 |
| CTSB | 3.46 | Cathepsin B |
| FAIM3 | 3.43 | Fas apoptotic inhibitory molecule 3 |
| CASP8 | 3.41 | Caspase-8 |
| SERPINB9 | 3.36 | Serpin peptidase inhibitor, clade B |
| GADD45B | 3.36 | Growth arrest and DNA-damage inducible, beta |
| RHOT2 | 2.71 | Ras homolog gene family, member T2 |
| RAF1 | 2.28 | v-raf-1 leukemia viral oncogene homolog 1 |
| NFKBIA | 2.27 | Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
| MCL1 | 2.25 | Myeloid cell leukemia sequence 1 (BCL2 related) |
| PDCD4 | 2.19 | Programmed cell death 4 |
| TP53BP2 | 2.19 | Tumor protein p53 binding protein, 2 |
| PRF1 | 2.16 | Perforin 1 |
| RELA | 2.13 | v-rel,p65 |
| TP53 | 0.50 | Tumor protein p53 |
| TNFAIP8 | 0.47 | TNF alpha-induced protein 8 |
| CASP3 | 0.46 | Caspase-3 |
| STAT1 | 0.45 | Signal transducer and activator of transcription 1 |
| IL2RB | 0.44 | Interleukin 2 receptor, beta |
| LCK | 0.41 | Lymphocyte-specific protein tyrosine kinase |
| FAS | 0.37 | Fas (TNFSF6) |
| SIVA | 0.33 | CD27-binding (Siva) protein |
| BAG2 | 0.23 | BCL2-associated athanogene 2 |
| BAX | 0.22 | BCL2-associated X protein |
| BCL2 | 0.21 | B-cell CLL |
| GZMA | 0.17 | Granzyme A |
| PRDX2 | 0.16 | Peroxiredoxin 2 |
| CASP6 | 0.15 | Caspase-6 |
| TNFSF10 | 0.15 | TNF superfamily, member 10 |
| TUBB | 0.10 | Tubulin, beta |