Table 1

Proportions of patients ultimately achieving major cytogenetic response by 12 months (12MMCyR)

Time point, responsen12MMCyR, no. (%)
Three months 
    Minor cytogenetic 15 10 (67) 
    Complete hematologic response or hematologic failure 42 3 (7) 
Six months 
    Minor cytogenetic 16 8 (50) 
    Complete hematologic response or hematologic failure 39 1 (3) 
Time point, responsen12MMCyR, no. (%)
Three months 
    Minor cytogenetic 15 10 (67) 
    Complete hematologic response or hematologic failure 42 3 (7) 
Six months 
    Minor cytogenetic 16 8 (50) 
    Complete hematologic response or hematologic failure 39 1 (3) 

Patients with no cytogenetic responses by 3 and 6 months were significantly less likely to reach 12MMCyR than patients with a minor cytogenetic response (P < .001 at both timepoints).