Trabecular morphological parameters (mean ± SEM) in the tibia of untreated and Sr-treated for 8 weeks mice by micro-CT or histomorphometric analysis
| . | Untreated . | Sr-treated . | % Difference . | P . |
|---|---|---|---|---|
| TV (mm3) | 1.63 ± 0.02 | 1.74 ± 0.06 | +6.23% | <.05 |
| BV (mm3) | 0.12 ± 0.02 | 0.17 ± 0.02 | +36.55% | <.01 |
| BV/TV | 7.21 ± 1.11 | 9.73 ± 0.83 | +30.57% | <.01 |
| TS (mm2) | 10.16 ± 0.18 | 10.79 ± 0.35 | +6.01% | <.05 |
| BS (mm2) | 9.44 ± 1.69 | 11.47 ± 1.25 | +20.33% | .1 |
| BS/TV (1/mm) | 5.79 ± 1.09 | 6.58 ± 0.54 | +14.22% | .24 |
| Tb.Th (mm) | 0.05 ± 0.004 | 0.06 ± 0.002 | +10.29% | <0.05 |
| Tb.Sp (mm) | 0.32 ± 0.06 | 0.31 ± 0.03 | +0.83% | .1 |
| Tb.N (1/mm) | 1.40 ± 0.27 | 1.70 ± 0.15 | +20.61% | .1 |
| Tb.Pf (1/mm) | 28.09 ± 1.57 | 21.90 ± 0.88 | −24.69% | <.001 |
| Ob. N* | 23.22 ± 3.36 | 40.33 ± 8.01 | +53.85% | <.05 |
| Ob.N/BS* | 4.71 ± 1.42 | 7.67 ± 0.49 | +47.81% | <.05 |
| . | Untreated . | Sr-treated . | % Difference . | P . |
|---|---|---|---|---|
| TV (mm3) | 1.63 ± 0.02 | 1.74 ± 0.06 | +6.23% | <.05 |
| BV (mm3) | 0.12 ± 0.02 | 0.17 ± 0.02 | +36.55% | <.01 |
| BV/TV | 7.21 ± 1.11 | 9.73 ± 0.83 | +30.57% | <.01 |
| TS (mm2) | 10.16 ± 0.18 | 10.79 ± 0.35 | +6.01% | <.05 |
| BS (mm2) | 9.44 ± 1.69 | 11.47 ± 1.25 | +20.33% | .1 |
| BS/TV (1/mm) | 5.79 ± 1.09 | 6.58 ± 0.54 | +14.22% | .24 |
| Tb.Th (mm) | 0.05 ± 0.004 | 0.06 ± 0.002 | +10.29% | <0.05 |
| Tb.Sp (mm) | 0.32 ± 0.06 | 0.31 ± 0.03 | +0.83% | .1 |
| Tb.N (1/mm) | 1.40 ± 0.27 | 1.70 ± 0.15 | +20.61% | .1 |
| Tb.Pf (1/mm) | 28.09 ± 1.57 | 21.90 ± 0.88 | −24.69% | <.001 |
| Ob. N* | 23.22 ± 3.36 | 40.33 ± 8.01 | +53.85% | <.05 |
| Ob.N/BS* | 4.71 ± 1.42 | 7.67 ± 0.49 | +47.81% | <.05 |
TV indicates tissue volume; BV, bone volume; TS, tissue surface; BS, bone surface; BS/TV, percentage of bone surface; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; Tb.N, trabecular number; Tb.Pf, trabecular pattern factor; Ob.N, osteoblast number; Ob.N/BS, osteoblast number per bone surface.
Histomorphometric analysis.