Poor prognostic parameters that may necessitate treatment
| Parameters . |
|---|
| Clinical |
| Prematurity |
| Ascites |
| Bleeding |
| Laboratory |
| White blood cells > 100 × 109/L |
| Severe coagulopathy |
| Progressive liver failure |
| No complete remission by 3 mo |
| Parameters . |
|---|
| Clinical |
| Prematurity |
| Ascites |
| Bleeding |
| Laboratory |
| White blood cells > 100 × 109/L |
| Severe coagulopathy |
| Progressive liver failure |
| No complete remission by 3 mo |
Poor prognostic parameters that may necessitate treatment with low-dose cytarabine in Down syndrome patients with transient myeloproliferative disease. Compiled from Massey et al,13 Klusmann et al,14 and Muramatsu et al.15