Patient characteristics
. | Mother donor, n = 47 . | Father donor, n = 71 . | P . | ||
---|---|---|---|---|---|
n . | % . | n . | % . | ||
Transplantation center | |||||
Perugia | 37 | 78.8 | 53 | 74.6 | .61 |
Pavia | 10 | 21.2 | 18 | 25.4 | |
Disease | |||||
Acute lymphoblastic leukemia | 24 | 51.1 | 43 | 60.6 | .31 |
Acute myeloid leukemia | 23 | 48.9 | 28 | 39.4 | |
Disease status at transplantation | |||||
Remission | 33 | 70.2 | 34 | 47.9 | .02 |
Relapse | 14 | 29.8 | 37 | 52.1 | |
Patient sex | |||||
Male | 25 | 53.2 | 45 | 63.4 | .27 |
Female | 22 | 46.8 | 26 | 36.6 | |
KIR ligand mismatch | |||||
Yes | 21 | 44.7 | 19 | 26.8 | .13 |
No | 20 | 42.6 | 40 | 56.3 | |
Not assessed | 6 | 12.8 | 12 | 16.9 | |
Median patient age at transplantation, range | 19 | 2-52 | 17 | 2-41 | .18 |
Median donor age, range | 45 | 28-66 | 45 | 21-70 | .92 |
CMV serology | |||||
Donor positive/recipient positive | 38 | 80.9 | 54 | 76.1 | .92 |
Donor positive/recipient negative | 5 | 10.6 | 8 | 11.3 | |
Donor negative/recipient positive | 2 | 4.3 | 3 | 4.2 | |
Donor negative/recipient negative | 1 | 2.1 | 4 | 5.6 | |
Not assessed | 1 | 2.1 | 2 | 2.8 | |
Graft composition, median, SD | |||||
CD34 (106/kg) | 12.1 | 7.7 | 14.5 | 9.3 | .22 |
CD3 (104/kg) | 1.0 | 1.1 | 1.0 | 3.4 | .79 |
Year of transplantation, median (range) | 2002 (1993-2006) | 1999 (1993-2006) | .22 |
. | Mother donor, n = 47 . | Father donor, n = 71 . | P . | ||
---|---|---|---|---|---|
n . | % . | n . | % . | ||
Transplantation center | |||||
Perugia | 37 | 78.8 | 53 | 74.6 | .61 |
Pavia | 10 | 21.2 | 18 | 25.4 | |
Disease | |||||
Acute lymphoblastic leukemia | 24 | 51.1 | 43 | 60.6 | .31 |
Acute myeloid leukemia | 23 | 48.9 | 28 | 39.4 | |
Disease status at transplantation | |||||
Remission | 33 | 70.2 | 34 | 47.9 | .02 |
Relapse | 14 | 29.8 | 37 | 52.1 | |
Patient sex | |||||
Male | 25 | 53.2 | 45 | 63.4 | .27 |
Female | 22 | 46.8 | 26 | 36.6 | |
KIR ligand mismatch | |||||
Yes | 21 | 44.7 | 19 | 26.8 | .13 |
No | 20 | 42.6 | 40 | 56.3 | |
Not assessed | 6 | 12.8 | 12 | 16.9 | |
Median patient age at transplantation, range | 19 | 2-52 | 17 | 2-41 | .18 |
Median donor age, range | 45 | 28-66 | 45 | 21-70 | .92 |
CMV serology | |||||
Donor positive/recipient positive | 38 | 80.9 | 54 | 76.1 | .92 |
Donor positive/recipient negative | 5 | 10.6 | 8 | 11.3 | |
Donor negative/recipient positive | 2 | 4.3 | 3 | 4.2 | |
Donor negative/recipient negative | 1 | 2.1 | 4 | 5.6 | |
Not assessed | 1 | 2.1 | 2 | 2.8 | |
Graft composition, median, SD | |||||
CD34 (106/kg) | 12.1 | 7.7 | 14.5 | 9.3 | .22 |
CD3 (104/kg) | 1.0 | 1.1 | 1.0 | 3.4 | .79 |
Year of transplantation, median (range) | 2002 (1993-2006) | 1999 (1993-2006) | .22 |