Table 1 Altered expression of Ly49s in... | American Society of Hematology

Table 1

Altered expression of Ly49s in Lat^−/−, Lab^−/−, and Lab/Lat^−/− NK cells

Ly49	WT	LAT^−/−	LAB^−/−	LAB/LAT^−/−
Ly49D (4E5)*	50.4 ± 1.9†	25.9 ± 1.8*	47.8 ± 3.3	25.3 ± 1.1‡
Ly49G (4D11)	44.2 ± 0.5	52.6 ± 1.2*	35.0 ± 1.7*	41.8 ± 1.0
Ly49C/I (5E6)	46.8 ± 2.5	28.0 ± 2.9*	38.7 ± 3.4	23.6 ± 1.7*
Ly49A (YE148)	11.7 ± 0.9	4.8 ± 0.3*	6.6 ± 0.8*	2.5 ± 0.4*
Ly49A (A1)	14.4 ± 0.9	5.7 ± 0.6*	9.7 ± 0.7*	3.8 ± 0.2*

Ly49	WT	LAT^−/−	LAB^−/−	LAB/LAT^−/−
Ly49D (4E5)*	50.4 ± 1.9†	25.9 ± 1.8*	47.8 ± 3.3	25.3 ± 1.1‡
Ly49G (4D11)	44.2 ± 0.5	52.6 ± 1.2*	35.0 ± 1.7*	41.8 ± 1.0
Ly49C/I (5E6)	46.8 ± 2.5	28.0 ± 2.9*	38.7 ± 3.4	23.6 ± 1.7*
Ly49A (YE148)	11.7 ± 0.9	4.8 ± 0.3*	6.6 ± 0.8*	2.5 ± 0.4*
Ly49A (A1)	14.4 ± 0.9	5.7 ± 0.6*	9.7 ± 0.7*	3.8 ± 0.2*

WT indicates wild-type.

Antibody used for the indicated Ly49.

Data reflect the percentage of NK1.1⁺CD3⁻ NK cells expressing the indicated Ly49 plus or minus SEM and reflect 3 to 5 independent analyses.

P < .01 relative to WT by Student 2-tailed t test.