Table 4 CCyR and MMR rates by PK... | American Society of Hematology

Table 4

CCyR and MMR rates by PK category, based on day 29 steady-state imatinib trough levels

Outcomes	Quartile 1 (95% CI)	Quartiles 2 and 3 (95% CI)	Quartile 4 (95% CI)
CCyR, n	87	178	86
1 y, %	59 (48-70)	71 (64-78)	73 (63-83)
2 y, %	73 (63-83)	80 (73-86)	84 (75-92)
5 y, %	83 (73-92)	88 (83-94)	93 (87-99)
*CCyR patients included in analysis: MMR, n**	57	138	70
1 y†, %	43 (28-59)	56 (47-66)	55 (41-68)
2 y‡, %	63 (49-78)	78 (69-86)	86 (76-96)

Outcomes	Quartile 1 (95% CI)	Quartiles 2 and 3 (95% CI)	Quartile 4 (95% CI)
CCyR, n	87	178	86
1 y, %	59 (48-70)	71 (64-78)	73 (63-83)
2 y, %	73 (63-83)	80 (73-86)	84 (75-92)
5 y, %	83 (73-92)	88 (83-94)	93 (87-99)
*CCyR patients included in analysis: MMR, n**	57	138	70
1 y†, %	43 (28-59)	56 (47-66)	55 (41-68)
2 y‡, %	63 (49-78)	78 (69-86)	86 (76-96)

Overall, 265 patients who had achieved CCyR had available PCR data as well as PK samples.

Including 209 patients who had achieved CCyR within 1 year and had PCR data and PK samples.

Including 225 patients who had achieved CCyR within 2 years and had PCR data and PK samples.