Table 2 Statistical analysis of tumor... | American Society of Hematology

Table 2

Statistical analysis of tumor growth in BALB/c wildtype, CD1KO, and Jα18KO mice inoculated with NS0-V or NS0-CD1 cells and treated with an isotype control or anti-CD1d mAb (n = 8 mice/group)*

Tumor and mouse group†	In vivo CD1d block
	Isotype control		Anti-mouse CD1d
	P	Significance‡	P	Significance
NS0-V with wildtype and CD1KO	.144	NS§	.843	NS
NS0-V with wildtype and Jα18KO	.021	S¶	.779	NS
NS0-V with CD1KO and Jα18 KO	<.001	S	.612	NS
NS0-CD1 with wildtype and CD1KO	.283	NS	.846	NS
NS0-CD1 with wildtype and Jα18 KO	.040	S	.926	NS
NS0-CD1 with CD1KO and Jα18KO	.006	S	.943	NS
Wildtype with NS0-V and NS0-CD1	.609	NS	.665	NS
CD1KO with NS0-V and NS0-CD1	.317	NS	.690	NS
Jα18KO with NS0-V and NS0-CD1	.364	NS	.943	NS

Tumor and mouse group†	In vivo CD1d block
	Isotype control		Anti-mouse CD1d
	P	Significance‡	P	Significance
NS0-V with wildtype and CD1KO	.144	NS§	.843	NS
NS0-V with wildtype and Jα18KO	.021	S¶	.779	NS
NS0-V with CD1KO and Jα18 KO	<.001	S	.612	NS
NS0-CD1 with wildtype and CD1KO	.283	NS	.846	NS
NS0-CD1 with wildtype and Jα18 KO	.040	S	.926	NS
NS0-CD1 with CD1KO and Jα18KO	.006	S	.943	NS
Wildtype with NS0-V and NS0-CD1	.609	NS	.665	NS
CD1KO with NS0-V and NS0-CD1	.317	NS	.690	NS
Jα18KO with NS0-V and NS0-CD1	.364	NS	.943	NS

Mice were inoculated with 10⁷ tumor cells/mouse and 50 μg of isotype or anti-mouse CD1d mAb on days −1, 5, 10, 20, 30, 40, and 50 intraperitoneally.

†

Comparisons were made between the different combinations of groups in order to determine the statistical significance of the analyses.

‡

The P values are based on the log-rank test comparing either 2 groups of mice with 1 cell line or 2 cell lines with 1 group of mice as indicated.

Not significant.

Significant (entries in bold).

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