Table 5

Association between percentage change in FLC* and urine protein in patients with abnormal baseline FLC† by baseline renal function status: Spearman correlation coefficient (P)

Urine M-spike
Urine total protein
Overall populationNormal renal functionAbnormal renal functionOverall populationNormal renal functionAbnormal renal function
Urine-only patients plus serum and urine patients, n 101 81 20 148 119 29 
    iFLC .60 (<.001) .67 (<.001) .55 (.01) .48 (<.001) .48 (<.001) .62 (<.001) 
    dFLC .60 (<.001) .66 (<.001) .61 (.004) .46 (<.001) .47 (<.001) .55 (.002) 
    rFLC .40 (.001) .43 (<.001) .27 (.3) .32 (.003) .30 (.001) .42 (.003) 
Urine-only patients, n 32 26 6 37 32 5 
    iFLC .58 (<.001) .69 (.001) .49 (.3) .51 (.001) .54 (.002) .70 (.2) 
    dFLC .58 (<.001) .69 (.001) .49 (.3) .51 (.001) .54 (.001) .70 (.2) 
    rFLC .54 (.002) .61 (.001) .31 (.5) .55 (<.001) .54 (.001) .70 (.2) 
Serum and urine patients, n 69 55 14 111 87 24 
    iFLC .62 (<.001) .65 (<.001) .58 (.03) .49 (<.001) .48 (<.001) .62 (.001) 
    dFLC .62 (<.001) .64 (<.001) .62 (.02) .49 (<.001) .46 (<.001) .53 (.007) 
    rFLC .37 (.002) .38 (.004) .28 (.3) .28 (.003) .25 (.02) .37 (.08) 
Urine M-spike
Urine total protein
Overall populationNormal renal functionAbnormal renal functionOverall populationNormal renal functionAbnormal renal function
Urine-only patients plus serum and urine patients, n 101 81 20 148 119 29 
    iFLC .60 (<.001) .67 (<.001) .55 (.01) .48 (<.001) .48 (<.001) .62 (<.001) 
    dFLC .60 (<.001) .66 (<.001) .61 (.004) .46 (<.001) .47 (<.001) .55 (.002) 
    rFLC .40 (.001) .43 (<.001) .27 (.3) .32 (.003) .30 (.001) .42 (.003) 
Urine-only patients, n 32 26 6 37 32 5 
    iFLC .58 (<.001) .69 (.001) .49 (.3) .51 (.001) .54 (.002) .70 (.2) 
    dFLC .58 (<.001) .69 (.001) .49 (.3) .51 (.001) .54 (.001) .70 (.2) 
    rFLC .54 (.002) .61 (.001) .31 (.5) .55 (<.001) .54 (.001) .70 (.2) 
Serum and urine patients, n 69 55 14 111 87 24 
    iFLC .62 (<.001) .65 (<.001) .58 (.03) .49 (<.001) .48 (<.001) .62 (.001) 
    dFLC .62 (<.001) .64 (<.001) .62 (.02) .49 (<.001) .46 (<.001) .53 (.007) 
    rFLC .37 (.002) .38 (.004) .28 (.3) .28 (.003) .25 (.02) .37 (.08) 

Data are correlation coefficients (P) except where shown.

*

Percent change = (2-month − baseline)/baseline.

†

Abnormal ratio and dFLC ≥ 5 mg/dL.

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